Male Development

Question 1

What protein is produced when the SRY gene is expressed?

Answer 1

Testis Determining Factor (TDF)

Question 2

Sertoli cells produce what hormone?

Answer 2

Anti-Mullerian Hormone (or Mullerian Inhibiting Substance)

Question 3

Leydig cells produce what hormone?

Answer 3

Testosterone

Question 4

Syncytiotrophoblasts produce this hormone

Answer 4

Human Chorionic Gonadotropin

Question 5

Human Chorionic Gonadotropin stimulates ____________ cells to produce _______________

Answer 5

Leydig, Testosterone

Question 6

Defective MIS receptors result in ______________ syndrome.

Answer 6

Persistent Mullerian Duct

Question 7

Complications of Persistent Mullerian Duct Syndrome may include ____________ and ____________.

Answer 7

Cryptorchidism, sterility

Question 8

The presence of Anti-Mullerian Hormone results in _____________________.

Answer 8

Degeneration of the Mullerian duct.

Question 9

Testosterone signals the mesonephric duct to ________ and _________.

Answer 9

Survive, grow

Question 10

The conversion of testosterone to dihydrotestosterone by 5-alpha-reductase is important for the development of these glands: __________, _________, __________.

Answer 10

Prostate, seminal vesicle, bulbourethral

Question 11

Germ layers that make up the genital tubercle

Answer 11

Ectoderm, lateral plate mesoderm, endoderm

Question 12

The prostate gland develops from the _________ epithelium of the _________.

Answer 12

Endodermal, urogenital sinus (pelvic portion)

Question 13

The bulbourethral gland develops from the _______ epithelium of the _________.

Answer 13

Endodermal, urogenital sinus (pelvic portion)

Question 14

The seminal vesicle develops as a bulbous swelling from the ___________.

Answer 14

Mesonephric duct

Question 15

The Mullerian ducts degenerate via the active process of ______________.

Answer 15

apoptosis

Question 16

Due to the concentration gradient of Anti-Mullerian Hormone, the Mullerian duct degenerates in a _______ to _________ direction.

Answer 16

cranial, caudal

Question 17

The elongation and subsequent convolution of the portion of the mesonephric duct closest to the developing testes forms the ______________.

Answer 17

epididymis

Question 18

Under the influence of the products of TDF expression, the cells of the mesothelium that have penetrated the gonadal ridge and enveloped the PGCs differentiate into _________________.

Answer 18

Sertoli cells

Question 19

While the endodermal epithelium of the UG sinus forms the glandular portion of the prostate, the _________ differentiates into the connective tissue and ___________ of the prostate.

Answer 19

mesenchyme, smooth muscle

Question 20

Prior to migration along the dorsal mesentery, the primordial germ cells are located in _________________ close to the ___________.

Answer 20

endoderm of the yolk sac, allantois

Question 21

The rete testis is the anastomoses of the ________ and the ________.

Answer 21

straight tubules, efferent ducts

Question 22

After the testis cords separate from the epithelium, a thick, fibrous layer of connective tissue called the ____________ separate the cords from the surface epithelium.

Answer 22

tunica albuginea