Male Anatomy Flashcards

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1
Q

What is the blood-testis barrier, and why is it important?

A

Formed by Sertoli cells, it protects sperm from immune attack by separating them from the systemic circulation.

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2
Q

What are the roles of Leydig and Sertoli cells?

A

Leydig cells produce testosterone, while Sertoli cells nourish developing sperm and regulate their maturation

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3
Q

What is cryptorchidism, and what are its consequences?

A

Cryptorchidism is the failure of testes to descend, which can impair spermatogenesis and increase the risk of testicular cancer.

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4
Q

What is hypospadias, and how does it affect the penis?

A

Hypospadias is a condition where the urethral opening is abnormally positioned along the ventral side of the penis, potentially causing difficulty with urination or fertility.

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5
Q

How does the pampiniform plexus aid in testicular function?

A

It acts as a heat exchanger, cooling arterial blood to maintain an optimal temperature for spermatogenesis.

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6
Q

What is the function of the tunica albuginea in the testes?

A

It is a dense connective tissue layer that provides structural support and divides the testes into lobules.

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7
Q

What is the function of the epididymis?

A

It stores and matures sperm, which gain motility and fertilizing capability here.

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8
Q

How is the testicular temperature regulated?

A

The Dartos muscle and pampiniform plexus regulate temperature, keeping it 1°C below core body temperature for optimal sperm production.

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9
Q

Where do the testes originate during development?

A

The testes originate on the posterior wall of the abdominal cavity during development

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10
Q

How do the testes descend to their final position by birth?

A

By birth, the testes descend into the scrotum through the inguinal canal, which is part of the anterior abdominal wall.

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11
Q

What is the role of the gubernaculum in testicular descent?

A

The gubernaculum is a ligament that pulls the testes caudally, guiding them from the abdominal cavity into the scrotum.

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12
Q

How does the vas deferens relate to the testes?

A

The vas deferens follows the testis into the scrotum and connects the testis to the urethra, allowing sperm to pass through during ejaculation.

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13
Q

What are the key components of the testis in its fully developed form?

A

The testis is organized into two main components:

Tubular components – Sertoli cells, germ cells, and myoid cells.
Interstitial components – Leydig cells and capillaries.

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14
Q

What is the function of Leydig cells in the testis?

A

Leydig cells are located in the seminiferous tubules and are responsible for producing testosterone.

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15
Q

What is the role of Sertoli cells in the testis?

A

Sertoli cells support and nourish developing sperm, providing an environment for spermatogenesis (sperm production).

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16
Q

What layers surround the testis?

A

The testis is surrounded by several layers, including the tunica vaginalis and the tunica albuginea

17
Q

Where is sperm produced in the testis?

A

Sperm is produced in the seminiferous tubules of the testis.

18
Q

Why is the temperature of the scrotum important for sperm production?

A

The temperature of the scrotum is 1 degree Celsius below core body temperature, which is optimal for sperm production. This is regulated by the Dartos muscle.

19
Q

How does sperm move from the seminiferous tubules to the epididymis?

A

Sperm produced in the seminiferous tubules pass into the rete testis and then into the head of the epididymis.

20
Q

What does the spermatic cord contain?

A

The spermatic cord contains the vas deferens, testicular artery, and the pampiniform plexus of veins.

21
Q

What is testicular torsion, and why is it dangerous?

A

Testicular torsion occurs when the spermatic cord twists, disrupting the blood supply to the testis. This can cause severe pain and lead to testicular necrosis (death of testicular tissue) if not treated promptly.

22
Q

What is the blood-testis barrier, and what is its main function?

A

The blood-testis barrier divides the two sections of the seminiferous tubules, separating one section from the interstitial environment. Its main function is to limit the free exchange of water-soluble molecules and protect the sperm from the immune system by preventing them from being recognized as foreign.

23
Q

Why do sperm need protection from the immune system?

A

Sperm are genetically different from the male and express different surface antigens, so they can be identified as foreign by the immune system. The blood-testis barrier helps protect the sperm from immune attack.

24
Q

What cells form the blood-testis barrier?

A

The blood-testis barrier is formed by Sertoli cells, which are located in the seminiferous tubules

25
Q

What is the structure of the scrotum?

A

The scrotum is a single pouch that contains two testes. It has several layers, including (from outer to inner):

External fascia (from the external oblique aponeurosis)
Cremasteric fascia (from the internal oblique muscle)
Internal spermatic fascia (from the transversalis fascia)

26
Q

What does each vas deferens connect to, and what is formed at this junction?

A

Each vas deferens connects with the duct from a seminal gland (which produces seminal fluid) to form an ejaculatory duct. The ejaculatory duct contains semen, which is a mixture of sperm and seminal fluid.

27
Q

Where do the ejaculatory ducts drain, and what is the final passage for semen?

A

The right and left ejaculatory ducts join within the prostate gland, just inferior to the bladder. The ejaculatory ducts then drain into the urethra, which is the final passage for semen, exiting the body through the external urethral meatus of the penis.

28
Q

What is the epididymis, and what is its role in sperm development?

A

The epididymis is a long, coiled tube located on the posterior surface of each testis. It is the site of sperm maturation and storage, where sperm acquire motility and the ability to fertilize an egg.

29
Q

Where are the seminal vesicles located, and what is their function?

A

The seminal vesicles are paired glands located behind the bladder. They secrete a fluid rich in fructose, which provides energy for sperm. This fluid also contains prostaglandins, which aid sperm motility and stimulate smooth muscle contractions in the female reproductive tract to help sperm reach the egg.

30
Q

What makes up the bulk of semen?

A

The fluid from the seminal vesicles makes up the bulk of semen. It is rich in fructose and contains prostaglandins to support sperm function.

31
Q

What is the function of the prostate gland in semen production?

A

The prostate gland secretes a thin, milky fluid that contains enzymes, citrate, and prostate-specific antigen (PSA). This fluid helps liquefy semen after ejaculation, which enhances sperm motility and facilitates sperm movement through the female reproductive tract.

32
Q

Where is the prostate gland located?

A

The prostate gland is a walnut-sized gland located below the bladder, surrounding the urethra.