Male Flashcards

1
Q
Which change is least likely effect of excess exogenous testosterone (abusing steroids)? 
A. acne
B. inc muscle mass
C. inc bone mass
D. anemia
A

D. Anemia

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2
Q

Low serum T with low FSH/LH and high GnRH suggests

A

Secondary hypogonadism

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3
Q

Spermatogenesis occurs within the

A

seminiferous tubules

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4
Q

MC genetic cause of secondary hypogonadism

A

Kallmann syndrome

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5
Q
What is true of Sertoli cells? 
A. lack aromatase
B. found in ovarian stroma
C. found in interstitial space between seminiferous tubules
D. secrete primarily androgens
E. respond primarily to FSH
A

E. respond primarily to FSH

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6
Q

Which route of T administration poses greatest risk for liver damage?

A

PO tablet

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7
Q
What is not true of aromatase?
A. converts estrogens into androgens
B. levels rise with age
C. inhibitors may be used in breast cancer treatment
D. is an intracellular CYP450 enzyme
E. widely present in adipose
A

A. coverts estrogens into androgens

other way around

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8
Q
5-alpha reductase inhibitors are used in the treatment of all of the following except: 
A. BPH
B. androgenic alopecia
C. prostate cancer
D. erectile dysfunction
A

E. erectile dysfunction

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9
Q

MOA of Lupron

A

Interrupts pulsatile rhythm of GnRH, leading to dec FSH & LH

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10
Q
Klinefelter is associated with all except: 
A. Reduced testicular volume
B. GnRH insensitivity
C. Azoospermia
D. Accessory X chromosome
E. Gynecomastia
A

B. GnRH insensitivity

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