Malaria Flashcards

1
Q

Which type of disease

A

Protozoal disease - Plasmodium vivax

Transmitted female anopheles mosquito

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2
Q

Agents

A

VFMO

Plasmodium Vivax 70%

P.Flaciparam 30%

P.Malarie

P.Ovale

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3
Q

Life cycle

A

Human Asexual

Mosquito sexual

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4
Q

Asexual cycle

A

Sporozoites (from bite M to H)

Hepatic schizonts

Merozoites

Enters RBC trophozoites schizonts

Gametocytes

Enters stomach mosquito

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5
Q

Sexual cycle

A

Microgametes

Macrogametes

Zygote

Ookinate oocyte

Reaches salivary gland via body cavity

REPEAT

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6
Q

People more prone to malaria

A
Affects all ages 
In pregnancy risk more  
Complications-
IUD
Premature labour.
Abortion.
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7
Q

Resistant

A

New born infants

SCA

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8
Q

Transmission

A

Bite infected anopheles mosquito

Not infective unless sporozoites in sg

Accidentally hypodermic intramuscular or intravenous injection of blood or plasma

Person has malaria no blood donated until 3yrs afterwards

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9
Q

Stages

A

Cold

Hot

Sweating

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10
Q

1st stage

A

Lassitude
headache
nausea
chilly sensation

Last for 1hr

Parasite demonstrated in blood sample

Temp raise 39-49 c
Plus rapid weak

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11
Q

2nd

A
Burning hot 
Throws clothes 
Skin hot and dry 
Nausea 
headache 
Pulse full 
Respiratory inc 
2-6 hr
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12
Q

3rd

A

Fever down
Skin cold moist
2-4 hrs

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13
Q

API

A

Annual parasite incidence=

(Confirmed cases 1yr ÷ population under surveillance)×1000

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14
Q

Malaria control

A

DDT spray

Larvicide like temophose

Breeding site reduce

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15
Q

Diagnosis

A

Microscopy stained thick thin blood smear
RDT based on circulating parasite antigen

Bivalent f&V

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16
Q

Treatment

A

First line cholorquine
P.vivax C 25 mg/body wt 3days
Tab.Mefloquine resistant to C
Primaquine no to pregnant woman infants

17
Q

High risk

A

Day 1 Tab C 10mg/bwt 600 mg adult dose
Tab Prima Q 0.75 mg/kg 45 AD

Day 2 Tab C 10mg/kgbwt

Day 3 Tab C 5mg/kgbwt 300mg adult dose

18
Q

P.Falciparam

A

Treat with ACT
Arteminse based combination therapy
Artesunate 3days + sulphadoxine pyrimethamine 1 day
Single dose primaQ day2

S/E dark colour urine
Yellow conjunctiva
Abdominal pain

19
Q

In pregnancy treatment

A

1st T quinine

2nd & 3rd T - ACT