Malaria Flashcards
Mortality and morbidity
30-35%
Plasmodium vivas
Mortality
67-70%
Plasmodium falciparum
Benign
0.01-1%
Plasmodium malariae
Common in african countries
Plasmodium ovale
Palawan and mindanao
Plasmodium knowlesi
Population at risk for malaria
11,337,000
Incidence per 1000
0.48
Number of malaria deaths
536
Number of patient tested for malaria
444,668
Mother to fetus
Vertical transmission
Sexual contact
Horizontal transmission
Gold standard for diagnosis
Thick and thin smear
Not to be used in light infection
Thin smear
If degree of parasitemia is too low
Thick smear
Red staining substance
Chromatin dots
Bluish substance adjacent to red substance
Cytoplasm
Brown substance
Hemozoin
Stain used to identify malarian parasite.
Routine procedure
Wright and giemsa stain
Stain used to identify malarian parasite.
Mass staining
Field’s stain
Transfer stage
Infective stage
Produce tissue alteration, signs and symptoms
Pathogenic stage
Any stage seen by naked eye. Basis for diagnosis
Diagnostic stage
All stages seen in peripheral smear
Plasmodium vivaxl
Plasmodium vivax
Only strain that causes
Enlarged RBC
Plasmodium vivax
Ring form, no enlargement, 1chromatin dot
Young trophozoite
Plasmodium vivax
1/3 occupied by blue cytoplasm, irregular in shape
1 chromatin dot
There is RBC enlargement
Growing trophozoite
Plasmodium vivax
2/3 bluish cytoplasm occupied
1 chromatin dot
Mature trophozoite
Plasmodium vivax
2 chromatin dots
Young schizont
Plasmodium vivax
2-12 chromatin dots
Growing schizont
Plasmodium vivax
12-24 chromatin dots in cluster
Rupture in vivo
Release merozoites invading other RBC
Mature schizont
Plasmodium vivax
Being developed after several weeks
Infective stage
Gametocytes
Plasmodium vivax
In gametocytes, chromatin dots are now called
Chromatin granules
Female
Chromatin granules on periphery
Compacted edge
Macrogametocyte