malaria Flashcards
doxycycline counselling
take 1-2 days before entering endemic area and continue for 4 weeks
protect skin from sunlight
do not take ingestion remedies or meds containing fe/zn - leave 2 hour gap
take whole with plenty of fluid during meals while sitting or standing upright
how long before travel should you start taking mefloquine
2 weeks
how long before travel should you start taking malarone
1-2 days
how long before travel should you start taking doxycycline
1-2 days
how long after travel should you take malarone for
1 week
long term prophylaxis of chlorophine and proguanil
> 5years
long term prophylaxis of doxycycline
2 years
long term prophylaxis of malarone and mefloquine
1 year
Which antimalarials should be avoided in epilepsy
chloroquine
mefloquine
Which antimalarials should be avoided in renal impairment
proguanil
Which antimalarials should be avoided in eGFR <30
malarone
chloroquine
Which antimalarials can be considered in renal impairment
doxycycline or mefloquine
Which antimalarials can be considered in pregnany
chloroquine & proguanil
+folic acid 5mg with proguanil
Which antimalarials are CI in pregnancy
doxycycline - dental hyperplasia and tooth discolouration
mefloquine
malarone - if no other choice, can give in 2/3 trimester
When to start taking antimalarials if you’re on warfarin
2-3 weeks before
INR should be stable
How often should INR be monitored
before, 7 days after starting and completing the course
POM antimalarials
malarone
doxycycline
mefloquine (lariam)
P antimalarials
Proguanil (paludrine)
Chloroquine (avloclor)
Chloroquine + Proguanil
Doxycycline side effects
photosensitivity
oesophageal irritation
mefloquine side effects
neuro psych reactions
once daily antimalarials
malarone
doxycycline
proguanil
once weekly antimalarials
mefloquine
chloroquine
What’s used for F. malaria
quinine
malarone
riamet
What’s used for non-falciparum malaria
chloroquine
malarone ingredients
atovaquone + proguanil
