Malabsorbtion syndromes

Question 1

The major causes of fat malabsorption are…… celiac disease and chronic pancreatitis

Answer 1

1. celiac disease

2. chronic pancreatitis

Question 2

Diarrhea characterized…..

Answer 2

1. greasy, oily,
2. floating, and fatty,
3. particularly foul smell,

Question 3

sign and symptoms

Answer 3

1.weight loss because fat has the highest
caloric content of all the foods
2.malabsorption of the fat-soluble vitamins
A, D, E, and K.
3.Iron malabsorption
4. Vitamin B12 malabsorption

Question 4

clinical presentation

Answer 4

1. chronic diarrhea

2. celiac disease is dermatitis herpetiformis, a vesicular skin rash on the extensorsurfaces

Question 5

chronic pancreatitis diagnosis with….

Answer 5

• Chronic alcohol abuse (most common cause)ry of pain,
• History of pain, recurrent attacks of acute pancreatitis, weight loss
• Pancreatic calcifications on imaging
• Exocrine pancreatic insufficiency (steatorrhea)
• Diabetes

Question 6

If CT does not show calcifications, get ……

Answer 6

MRCP to detect abnormal pancreatic ducts.

Question 7

cystic fibrosis with chronic pancreatitis and……..

Answer 7

recurrent pneumonia, sinusitis, and infertility

Question 8

TTT of chronic pancreatitis

Answer 8

1. pancreatic enzymes
2. pain control with NSAID/acetaminophen
3. insulin for DM type1
4. not use narcotics for pain control

Question 9

Celiac Sprue is

Answer 9

secondary to ingestion of wheat, gluten, or related rye and barley proteins

Question 10

clinical presentation

Answer 10

• Chronic diarrhea or steatorrhea
• Bloating, weight loss, abdominal pain
• Pruritic papulovesicular rash on extensor surfaces (dermatitis herpetiformis)
• Isolated abnormalities in liver chemistry tests
• Unexpanded iron deficiency anemia (after a negative work up for GI bleed)
• Fat-soluble vitamin deficiencies
• Early onset osteoporosis
• Strong association with type 1 diabetes (should be screened)
• Malabsorption of thyroid hormone in patient with thyroiditis
• IBS-D

Question 11

diagnosis…

Answer 11

1.presence of antiendomysial and
anti-transglutaminase antibodies.
2.The most accurate test is a small bowel biopsy, which shows
flattening of villi to exclude lymphoma

Question 12

The single most sensitive test for Whipple’s disease is ….

Answer 12

PCR (+tropheryma)

Question 13

TTT

Answer 13

1.adhering to a gluten-free diet
2.Use dapsone when celiac
patients have dermatitis herpetiformis