Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Psychiatry > Major Side Effects > Flashcards

Major Side Effects Flashcards

1
Q

HAM side effects

A

antiHistamine: sedation, weight gain
antiAdrenergic: hypotension
antiMuscarinic: dry mouth, blurred vision, urinary retention

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

HAM side effects are seen with…

A

TCAs and low-potency antipsychotics (chlorpromazine, thorazine)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Serotonin syndrome

A

confusion, flushing, diaphoresis, tremor, myoclonic jerks, hyperthermia, hypertonicity, rhabdomyolysis, renal failure, death

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Serotonin syndrome is seen with…

A

SSRIs, MAOIs (especially the combination of)

  • drugs that inc serotonin may also be in OTC cough remedies
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Hypertensive crisis is seen with…

A

MAOIs plus foods with tyramine (red wine, cheese, chicken liver, cured meats) or plus sympathomimetics

  • causes a buildup of stored catecholamines
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Extrapyramidal side effects

A

Parkinsonism: mask like face, cogwheel rigidity, pill-rolling tremor, akathisia, agitation, dystonia (of neck, tongue, eyes, diaphragm)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Extrapyramidal side effects are seen with…

A

high-potency typical antipsychotics (haloperidol, fluphenazine)

  • occur within days of starting, reversible, but can be life-threatening
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What drugs are used to treat extrapyramidal symptoms produced by neuroleptics?

A

benzotropine (Cogentin, an anticholinergic), diphenhydramine (Benadryl), trihexyphenidyl (Artane)

occasionally pramipexole (dopamine agonist)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Hyperprolactinemia is seen with…

A

high potency traditional antipsychotics and risperidone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Tardive dyskinesia

A

choreoathetoid muscle movements (usually of mouth and tongue) ex. grimacing, tongue protrusion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Tardive dyskinesia is seen with…

A

after LONG-TERM antipsychotic use (especially high-potency typical antipsychotics)

  • may be irreversible
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Neuroleptic malignant syndrome

A

fever, tachycardia, hypertension, tremor, elevated creatine phosphokinase (CPK), “lead pipe” rigidity

  • MEDICAL EMERGENCY (20% mortality)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Neuroleptic malignant syndrome is seen with…

A

all antipsychotics (inc risk with high-potency traditional antipsychotics)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Cytochrome P450 (CYP450) inducers

A

smoking
carbamazepine
barbituates
St. John’s wort

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Cytochrome P450 (CYP450) inhibitors

A 
fluvoxamine
fluoxetine
paroxetine
duloxetine
sertraline
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What class of drugs can exacerbate Alzheimer’s disease?

A

anticholinergics

17
Q

What medications can make tardive dyskinesia worse?

A

Anticholinergics (benztropine/Cogentin) and diphenhydramine (Benadryl)

Psychiatry (7 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions