Major Neurocognitive Disorder Criteria

Question 1

A. Evidence of significant cognitive decline from a previous level of performance in one or more cognitive domains based on:
1. _________________________________
2. a substantial impairment in cognitive performance, preferably documented by standardized neuropsych testing or another quantified clinical assessment
B. The cognitive deficits interfere with independence in everyday activities (at a minimum requiring assistance with complex IADLs)
C. The cognitive deficits do not occur exclusively in the context of delirium
D. The cognitive deficits are not better explained by another mental disorder (MDD, schizophrenia)

Answer 1

A. Evidence of significant cognitive decline from a previous level of performance in one or more cognitive domains based on:

1. concern of the individual, a knowledgeable informant, or the clinician that there have been a significant decline in cognitive function; and
2. a substantial impairment in cognitive performance, preferably documented by standardized neuropsych testing or another quantified clinical assessment

Question 2

A. Evidence of significant cognitive decline from a previous level of performance in one or more cognitive domains based on:
1. concern of the individual, a knowledgeable informant, or the clinician that there have been a significant decline in cognitive function; and
2. _______________________________________
B. The cognitive deficits interfere with independence in everyday activities (at a minimum requiring assistance with complex IADLs)
C. The cognitive deficits do not occur exclusively in the context of delirium
D. The cognitive deficits are not better explained by another mental disorder (MDD, schizophrenia)

Answer 2

A. Evidence of significant cognitive decline from a previous level of performance in one or more cognitive domains based on:

1. concern of the individual, a knowledgeable informant, or the clinician that there have been a significant decline in cognitive function; and
2. a substantial impairment in cognitive performance, preferably documented by standardized neuropsych testing or another quantified clinical assessment

Question 3

A. _______________________________:
1. concern of the individual, a knowledgeable informant, or the clinician that there have been a significant decline in cognitive function; and
2. a substantial impairment in cognitive performance, preferably documented by standardized neuropsych testing or another quantified clinical assessment
B. The cognitive deficits interfere with independence in everyday activities (at a minimum requiring assistance with complex IADLs)
C. The cognitive deficits do not occur exclusively in the context of delirium
D. The cognitive deficits are not better explained by another mental disorder (MDD, schizophrenia)

Answer 3

A. Evidence of significant cognitive decline from a previous level of performance in one or more cognitive domains based on:

1. concern of the individual, a knowledgeable informant, or the clinician that there have been a significant decline in cognitive function; and
2. a substantial impairment in cognitive performance, preferably documented by standardized neuropsych testing or another quantified clinical assessment

Question 4

A. Evidence of significant cognitive decline from a previous level of performance in one or more cognitive domains based on:
1. concern of the individual, a knowledgeable informant, or the clinician that there have been a significant decline in cognitive function; and
2. a substantial impairment in cognitive performance, preferably documented by standardized neuropsych testing or another quantified clinical assessment
B. __________________
C. The cognitive deficits do not occur exclusively in the context of delirium
D. The cognitive deficits are not better explained by another mental disorder (MDD, schizophrenia)

Answer 4

B. The cognitive deficits interfere with independence in everyday activities (at a minimum requiring assistance with complex IADLs)

Question 5

A. Evidence of significant cognitive decline from a previous level of performance in one or more cognitive domains based on:
1. concern of the individual, a knowledgeable informant, or the clinician that there have been a significant decline in cognitive function; and
2. a substantial impairment in cognitive performance, preferably documented by standardized neuropsych testing or another quantified clinical assessment
B. The cognitive deficits interfere with independence in everyday activities (at a minimum requiring assistance with complex IADLs)
C. ____________________________
D. The cognitive deficits are not better explained by another mental disorder (MDD, schizophrenia)

Answer 5

C. The cognitive deficits do not occur exclusively in the context of delirium

Question 6

A. Evidence of significant cognitive decline from a previous level of performance in one or more cognitive domains based on:
1. concern of the individual, a knowledgeable informant, or the clinician that there have been a significant decline in cognitive function; and
2. a substantial impairment in cognitive performance, preferably documented by standardized neuropsych testing or another quantified clinical assessment
B. The cognitive deficits interfere with independence in everyday activities (at a minimum requiring assistance with complex IADLs)
C. The cognitive deficits do not occur exclusively in the context of delirium
D. __________________________

Answer 6

D. The cognitive deficits are not better explained by another mental disorder (MDD, schizophrenia)

Question 7

specified causes of major neurocognitive disorder

Answer 7

alzheimer's
frontotemporal degeneration
lewy body
vascular
TBI
substance/medication use
HIV
prion disease
parkinson's
huntingon's
another medical condition
multiple etiologies

Question 8

without behavioral disturbance

Answer 8

no clinically significant behavioral disturbance

Question 9

with behavioral disturbance

Answer 9

accompanied by clinically significant behavioral disturbance

• psychotic symptoms
• mood disturbance
• agitation
• apathy

Question 10

mild

Answer 10

difficulty with IADLs (housework, managing money)

Question 11

moderate

Answer 11

difficulty with ADLs (feeding, dressing)

Question 12

severe

Answer 12

fully dependent