Major Effects Flashcards
1
Q
IL-1
A
Activation phagocytes, co-stimulatiom lymphocytes, increasing adhesion molecules on endothelium, induction fever and sleep, increased prostaglandin production
2
Q
TNF-alpha
A
Activation of phagocytes, increasing adhesion molecules on endothelium, mobilisation of fat
3
Q
IL-6
A
Co-stimulation of lymphocytes, differentiation of B-lymphocytes, synthesis of acute phase proteins
4
Q
IL-12
A
Stimulating Th-1 differentiation, activation NK-cells
5
Q
IFN-alpha, IFN-beta
A
Inhibiting viral replication
6
Q
IFN-gamma
A
Inducing and enforcing MHC-II expression, increasing IL-2 receptor expression, activation of NK-cells, enforcing Fc-gamma-receptor expression on macrophages, increasing intracellulair killing of bacteria by macrophages, stimulating B-cell differentiation
