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Cytokines > Major Cytokines > Flashcards

Major Cytokines Flashcards

0
Q

G-CSF

A

Granulocytes hematopoeisis

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1
Q

Interferons

A

Interfere with viral replication

-IFN-alpha, IFN-beta, IFN-gamma

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2
Q

M-CSF

A

Macrophage hematopoeisis

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3
Q

SCF

A

Differentiation of BM cells

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4
Q

GM-CSF

A

Granulocyte/macrophage hematopoeisis

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5
Q

IL-3

A

Hematopoeisis

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6
Q

IL-6

A

Hematopoeisis

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7
Q

IL-7

A

Hematopoeisis

-bcells/tcells

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8
Q

IL-11

A

Hematopoeisis, platelets

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9
Q

IL-5

A

Hematopoeisis for eosinophils

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10
Q

TNF-alpha

A

Induces fever, pro inflammatory

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11
Q

TNF-beta

A

Lymphotoxin, proinflammatory

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12
Q

RANTES

A

Chemokine

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13
Q

Eotaxin

A

Chemokine - eosinophil specific

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14
Q

IL-8

A

Chemokine (CXCL8)

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15
Q

SDF-1

17
Q

IL-12

A

Drives TH1 formation from th0

18
Q

IL-17

A

Drives inflammation

19
Q

Bacterial septic shock & TSS

A

Overproduction of IL-1 & TNF-Alpha

20
Q

IL-4

A

Induces th0 to form th2

21
Q

Th1, TNF-B, IFN-gamma

A

Act on macrophages to induce cell mediated immunity

22
Q

Th2, IL-4, IL-5, IL-13

A

Act on b-cells to induce antibody mediated immunity

23
Q

IFN-alpha cytokine therapy

A

Hepatitis b, hep c, hairy cell leukemia, chronic myelogenous leukemia

24
Q

IFN-B cytokine therapy

A

Multiple sclerosis

25
Q

IFN-gamma cytokine therapy

A

Chronic granulomatous disease

26
Q

IL-13

A

Anti inflammatory

27
Q

IL-17

A

Inflammatory

28
Q

IL-23

A

Generation of T-reg

29
Q

TGF

A

Anti-inflammatory

30
Q

IL-1

A

Inflammatory

38
Q

IL-10

A

Proinflammatory cytokine

Cytokines (1 decks)

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