Major Categories of Cardiovascular Drugs and Their Indications Flashcards
What are the 11 major cardiovascular drug categories?
● Cardiac Glycosides
● Thiazide Diuretics
● Loop Diuretics
● Sodium Channel Blockers
● Aldosterone Antagonists
● Angiotensin II Receptor Blockers (ARBs)
● Beta-Blockers
● ACE Inhibitors
● Potassium Channel Blockers
● Nitrates
● Anti-platelet Drugs
Cardiac Glycosides example, indications, and mechanism?
Digoxin
Heart failure (HFrEF), atrial fibrillation
Increases myocardial contractility and slows AV node conduction
Thiazide Diuretics example, indications, and mechanism?
Hydrochlorothiazide
Hypertension, heart failure
Inhibits sodium reabsorption, reducing blood volume
Loop Diuretics example, indications, and mechanism?
Furosemide
Heart failure, hypertension w/ fluid retention
Inhibits sodium, potassium, and chloride reabsorption in the loop of Henle
Sodium Channel Blockers example, indications, and mechanism?
Lidocaine, Flecainide
Ventricular and atrial arrhythmias
Stabilizes abnormal electrical activity by blocking sodium channels
Aldosterone Antagonists example, indications, and mechanism?
Spironolactone
Heart failure, resistant hypertension
Blocks aldosterone, reducing sodium retention and blood pressure
Angiotensin II Receptor Blockers (ARBs) example, indications, and mechanism?
Losartan
Hypertension, heart failure, diabetic nephropathy
Blocks angiotensin II, reducing vasoconstriction and aldosterone secretion
Beta-Blockers example, indications, and mechanism?
Metoprolol, Carvedilol
Hypertension, heart failure, arrhythmias, post-MI
Blocks beta-adrenergic receptors, reducing heart rate and contractility
ACE Inhibitors example, indications, and mechanism?
Lisinopril
Hypertension, heart failure, post-MI, diabetic nephropathy
Inhibits ACE, reducing angiotensin II production and blood pressure
Potassium Channel Blocker example, indications, and mechanism?
Amiodarone
Atrial and ventricular arrhythmias
Blocks potassium channels, prolonging repolarization
Nitrates example, indications, and mechanism?
Nitroglycerin
Angina, acute heart failure
Dilates veins and coronary arteries, reducing myocardial oxygen demand
Antiplatelet Drugs exampls, indications, and mechanism?
Aspirin, Clopidogrel
Prevention of heart attacks, strokes, stent thrombosis
Inhibits platelet aggregation, reducing clot formation