Maintenance of Anaesthesia Flashcards
What are potential problems with ET tubes? how can they be prevented?
- occlusion of end of ET tube (prevented by Murphy’s eye)
- endobronchial intubation - mucus in the tube may cause occlusion and infection, ^ resistance and only ventilating one lung (don’t push too far!)
- compression of inside of tube or stretching of tracheal wall (listen for gas escaping until none escapes)
When can you intubate?
> suficient depth of anaesthesia
- eyes rotated ventrally
- minimal, sluggish palpebral reflex
- loose jaw tone
- no swallowing reflex
What side effects do anaesthetic agents have?
DOse dependant
- CV depression(v CO, vasodialtion, v BP)
- resp depression (v RR, v TV, v MV)
Do most GA provide anaesthesia?
No
except: KETAMINE
Why is analgesia required even if animal is unconcsious?
- prevent unconcious upregulation of pain processing pathways
What ROA are available for anaesthetic maintainence?
> IV - TIVA - Intermittent boluses - CRI > Inhalational > Both ("balanced technique) - partial intravenous anaesthesia (PIVA) > occasionally (rarely) single IM injection sufficient (eg darting wild animals)
Why must you be careful when intubating cts?
Laryngeospasm
- spray lidocaine “intubeaze”
- CAVE: easy to overdose -> local anaesthetic toxicity
What are the 6 aspects of balanced anaesthesia?
- minimise stress
- analgesia
- mm relaxation
- v amount of drugs (so use more types)
- v autonomic reflex activity
- unconciousness
Which GA drugs can be used for injectable maintainence of anaesthesia?
> best for CRI - propofol - alfaxolone > best for intermittent boluses - ketamine - thiopental
Which GA drugs can be used for inhalational anaesthesia?
- isoflurane and sevoflurane [licensed smallies]
- halothane [old fashioned]
- desflurane [new but expensive]
- N2O
- xenon
What 2 ways can TIVA be carried out?
> intermittent boluses
+ simpler, require less equipment
- swinging plane of anaesthesia so ^ risk toxicity
CRI
- need pump/cri infuser
+ TCI : calculate amount of drug to deliver by measuring plasma concentration, ie. minimum infusion rate (=MAC??)
How are most inhalational agents administered and removed?
Lungs
excpetion: halothane metabolised in liver
How may redistribution of inhalational agents affect anaesthesia?
- fat soluability -> slow recovery from long anaesthetic
- vessel-rich (brain, kidneys) v vessel-poor tissues (skin)
Which factors affect inhalational agent uptake?
Pressure gradient from vaporizer to brain
- vaporiser setting
- anaesthetic circuit volume
- alveoli (eg. pulmonary oedema)
- blood
- brain
> Brain concentration approximates alveolar concentration (equililbrium) so expirational concentration (End tidal concentration)
Which factors affect speed of induction?
- ^ partial pressure in lungs = high partial pressure in brain
- if agents v. soluable in blood will remain there -> v partial pressure in brain
- slower induction and recovery for more soluble agents
- CF. injectable agents which SHOULD be dissolvable in blood