Maintaining a balance Flashcards
Most organisms are active in a limited temperature range
- Ensures metabolism (sum of all chemical processes in a organism)
- By providing constant temp, chemical balance
- Effect→ Maintains optimum conditions for enzyme functioning
What are enzymes?
- Globular proteins
- Increase rate of reactions (catalyse)
- Unchanged at end of reaction
- Bind to substrate → active site
- Active site→ pocket (protein folds where substrates bind)
Chemical composition of enzymes
- Protein molecules (amino acid chain)
- Folded in a specific shape
- Enzymes acts on reactant molecule (substrate)
- Enzymes fit with substrate as specific location on surface of enzyme molecule (ACTIVE SITE)
Role of enzymes in metabolism; Acceleration of chemical reactions
- Catalysts→ speeds or slows reactions without temp change
- Heat damages tissues in cells
- Lower activation energy so reaction can occur quickly
Role of enzymes in metabolism; Lowering of activation energy
- Don’t produce activation energy; reduces amount needed
- Brings specific molecules together, instead of relying on random collision
Role of enzymes in metabolism; Action on specific substrates
- Only one particular enzyme can work on only one particular substrate molecules
- Active site is reciprocally shaped to bind with that molecule
- Not chemically changes in reaction→ can be reused
Enzyme characteristics; Temperature sensitive
- In cells function best at body temp
- Above 60℃→ stop working
- Heat causes hydrogen bonds to break → alters shape/structure
- Change affects active site→ not reciprocally shaped
- Temp too high/low → will denature
Enzyme characteristics; pH sensitive
- Own narrow pH range functions efficiently
- Levels outside optimum→ alters shape/stops functioning
- Most function at or near neutral
Enzyme characteristics; substrate specific
- Molecules specific→ act on only one type of substrate
- Each enzyme catalyses on particular reaction
- E.g. Rennin acts on protein in milk causing it to curdle
Induced fit model
- Enzyme molecule changes shape as substrate molecule approaches (molecules are flexible)
- Reaction occurs→ substrate is changed, product is released (enzyme returns to original form)
- E.g. gloved hand changes to catch ball; active site is palm, closes around ball when ball draws near
Lock and key model
- Simply fits into active site to form immediate reaction (not considered great explanation)
- Brings active site of both molecules into alignment; reaction occurs quickly
- Depends on unlikely event of random collisions between enzyme and substrate
- E.g. Like trying to get key in lock by throwing key at lock with eyes closed
First hand investigation; increased temperature (enzyme)
- Milk with rennin; curdled quickly (temp approx 37 0C)
- Temps higher or lower→ milk with rennin doesn’t curdle
- Temp higher or lower than optimum 37 0C→ rennin doesn’t react and curdle milk
First hand investigation; change in pH (enzyme)
- pH affects activity of catalase in potato tissue (has optimum pH)
- Height of foam measured when catalase put in hydrogen peroxide
- pH of 9 is optimum for catalase (average bubble height was higher)
Identify the pH as a way of describing the acidity of a substance
- pH scale→ indicates acidity
- Lower value= acidic, Higher value = alkaline
Explain why the maintenance of a constant internal environment is important for optimal metabolic efficiency
- Must be stable → so enzymes can function, metabolism efficiency maintained
- Enzymes are sensitive to changes, only work in narrow range of pH and temp.
- Small variations from narrow range→ small decreases in activity
- Larger variation from narrow range → reduced metabolic efficiency
Stimuli (negative feedback model)
Increased or decreased body temp (E.g. Hot or cold surroundings, exercise)
Co-ordinating (control) centre (negative feedback model)
Hypothalamus detects change and activates cooling or warming mechanisms
Effectors (negative feedback model)
High temp:
- Skin vessels dilate (blood carries heat to skin surface)
- Sweat glands (Increase evaporative cooling)
Low temp:
- Skin vessels constrict (reduces heat loss from skin surface)
- Skeletal muscles activates (shivering generates heat)
Negative feedback loop (negative feedback model)
Body temp decreases or increases, hypothalamus shuts off warming/cooling mechanism
Describe homoeostasis, as the process by which organisms maintain a relatively stable internal environment
- Maintenance of constant or almost constant internal state, regardless of external environmental change
- Body regulates respiratory games, protect against pathogens, maintain salt and fluid balance, constant body temp, energy and nutrient supply
- Kept at constant level regardless of environmental change: body temp, blood pH, water/salt balance, blood pressure, oxygen and carbon dioxide concentration.
Explain that homeostasis consists of 2 stages:
- Detecting changes from the stable state - Counteracting changes from the stable state
- Any internal environment deviation must be quickly corrected. Counteract; use corrective mechanism
Stage 1: Detect change from stable state: Receptors detect change. E.g. Thermoreceptors in skin
Stage 2: Counteract change: Effector (muscle or gland) receives message to counteract change. Response is initiated to reverse change and restore body to stable.
- E.g. Muscles shiver to generate heat
- If variation exceeds normal range; NEGATIVE FEEDBACK counteracts change, returns body to homeostasis
Analyse information from secondary sources to describe adaptations and responses that have occurred in Australian organisms to assist temperature regulation
GENERATE/RETAIN HEAT
Generate heat:
- Shivering: Rapid muscle contractions
- Increased metabolism; Activity of thyroid gland stimulated, speeds up metabolism
Retain heat:
- Raised hair: raps warm air, reduces heat loss by convection. Muscles contract
- Vasoconstriction: Blood vessels construct so heat carried in blood is redirected to core of body, prevents heat loss from body surface
Analyse information from secondary sources to describe adaptations and responses that have occurred in Australian organisms to assist temperature regulation
RELEASE HEAT/GENERATE LESS HEAT
Release heat:
- Vasodilation: Arterioles expand, blood directed to body surface, heat lost by radiation, convection
- Sweating: liquid secreted onto skin, heat removed to evaporate liquid
Generate less heat:
- Decreased metabolism: Thyroid gland lowers metabolism, generates less heat
- Flattened hairs: Laid flat, increases heat loss
Outline the role of the nervous system in detecting and responding to environmental changes
- Function of nervous system→ coordination
- Receptors; Thermoreceptors, hypothalamus detects change → converts to message, travels along nerves in CNS (brain, spinal cord)
- Control centre: CNS processes info about change in specific parts of brain
- Motor nerves; Carry info as nerve impulses from CNS to effectors
- Effectors: Muscle or gland receives impulses, instruct effectors to respond
- Response; Counteracts original change; ensures homeostasis
Identify the broad range of temperatures over which life is found compared with the narrow limits for individual species
- Living creatures can survive temps of -70℃ (poles), high as 56℃ (deserts), 350℃ ( hot vents in sea)
- Individual species need much narrower range of temp (have optimum temp they function at)
- Tolerance range; temp range species can survive, usually few degrees outside of optimum
- Vast range of temps→ beneficial for species diversity
Endothermic
Maintain constant internal temp; using internal metabolism to generate heat (mammals)
Ectothermic
Body temp governed by external heat sources, environment regulates temp (reptiles)
Compare responses of named Australian ectothermic and endothermic organisms to changes in the ambient temperature and explain how these responses assist temperature regulation :ECTOTHERMIC
Blue Tongue Lizard:
- Cold weather→ remain inactive (buried in shelter) lowers metabolic rate→ conserve energy
- Sunny days→ emerge to bask→ raises temp
Compare responses of named Australian ectothermic and endothermic organisms to changes in the ambient temperature and explain how these responses assist temperature regulation: ENDOTHERMIC
Red Kangaroo:
- Hottest part of day→ seek shade, tail and hind legs shaded by rest of body (reduces surface are exposed to sun)
- Lowers body temp
Identify some responses of plants to temperature change
Leaf Fall; Hot conditions→ plants drop leaves (reduces surface area to sun, reduces water loss through transpiration)
Shiny Leaves: Reflect solar radiation→ reduces heat absorbed
Orientation: Vertical orientation→ reduces surface area to sun, reduces amount of heat exposed to)
Ice formation between cells:Temps below freezing→ ice form in cells, forms in gaps between plant cells; cell walls protects cytoplasm being pierced by ice crystal→ cell survives
PLANTS AND ANIMALS TRANSPORT DISSOLVED NUTRIENTS AND GASES IN A FLUID MEDIUM
- Transport system; distributes food/oxygen to cells, removes carbon dioxide and waste
- Blood; fluid transport medium; contains 3 types of cells
- RBC: Carry oxygen, maintain pH of blood
- WBC: Part of immune system, protects against invading organism
- Platelets: Clotting of blood, stops blood loss
- Plasma; Makes up most blood volume; carries nutrients, gases etc
Identify the form(s) in which each of the following is carried in mammalian blood:
- Carbon dioxide
- Cellular respiration product carried to lungs
- 70% as hydrogen carbonate ions, 7% as plasma, 23% combined with haemoglobin
- Travels in RBC, plasma
Identify the form(s) in which each of the following is carried in mammalian blood:
- Oxygen
- Carried from lungs to heart, body tissues
- 98.5% as heamoglobin in RBC, 1.5% dissolved in plasma
Identify the form(s) in which each of the following is carried in mammalian blood:
- Water
- Reabsorbed from nephron to body cells
- Travels in plasma as water molecules
Identify the form(s) in which each of the following is carried in mammalian blood:
- Salts
- Reabsorbed from nephrons to all body cells.
- Dissolved in plasma as ions
Identify the form(s) in which each of the following is carried in mammalian blood:
- Lipids
- Absorbed across villi wall of small intestine to veins in shoulder,
- As fatty acids, glycerol dissolved in plasma