maguire

Question 19

what is the difference between FMRI and MRI?

Answer 19

FMRI looks at the brain and its blood flow to see activity in the brain
MRI looks at only the structure

Question 20

what were the two scanning techniques done after the MRI ?

Answer 20

VBM
pixel counting

Question 21

what is VBM

Answer 21

it is a statistical tech used to measure grey matter within the brain

Question 22

how does VBM work

Answer 22

it works by dividing the brain into 3D units and comparing grey matter differences between groups e.g TD and NTD

Question 23

what is pixel counting

Answer 23

it is a more manual way instead of looking at the whole brain they just look at the hippocampus

Question 24

how is pixel counting carried out

Answer 24

a specialist blind to participants
counted pixels making up the hippocampus
in a mri scan to estimate its volume
to compare anterior posterior and the hippocampus (inside and out)

Question 25

participants

Answer 25

-taxi drivers 16 right handed male london taxi drivers age 32-62 mean age of 44 all men had taxi drivers for atleasr 1.5 years mean time as a taxi driver - 14.3 years range - 1.5-42 years alll were healthy -non taxi drivers 50 right handed males age 32-62 who had been scanned for the MRI database no one with health problems was included

Question 26

procedure

Answer 26

structural mri scans were obtained from both taxi drivers and non 2. two image analysis methods were used to analyse the data/scans VBM identifies the grey matter in different parts of the brain pixel counting - 2D model specialist counts pixels this identifies the volume of the hippocampus -the specialist was blind to whether the participant was a taxi driver or not 3. comparison were made between the findings from the scans of the taxi driver and those of non taxi drivers