Magnesium Flashcards
1. To know causes of Hypomagnesemia and the Treatment. 2. To know causes of Hypermagnesemia and the Treatment 2.
What are high/intermediate sources of magnesium?
High - green leafy veggies
Intermediate - meats, starches and milk
What is the normal serum mg level?
1.8 - 2.3mg/dl. [1.5 – 2.5 mEq/L]
what organs regulate ICF & ECF Mg?
Kidney, GI tract and bone (50-60% of Mg found in bone.
What association do PTH, decreased excretion of Na or Ca, and fluid volume deficit have on the excretion of Mg?
PTH - decrease excretion of Mg.
Decreased excretion of Na or Ca - decrease excretion of Mg.
What are the main causes of Hypomagnesemia?
GI loss Intracellular shift Decreased GI absorption Increased urinary loss. Prolong administration of MG free PN
Two example of increased GI loss
Prolong vomiting or gastric suction
Prolong diarrhea
Factors/condition that cause intracellular shift of Mg.
Insulin
Catecholamine
Hungry bone syndrome
Examples of malabsorption syndrome
Cancer
Colitis
Pancreatic insufficiency
Surgical resection of GI tract
Described the process in diabetic Ketoacidosis (DKA) or poorly diabetes that causes hypokalemia?
Mg moves out of cell and loss in the urine because of osmostic diuresis from glucosuria
Describe the process where hypomagnesemia may cause hypocalcemia.
Hypomagnesemia may cause hypocalcemia by reducing the release and the action of PTH, which is a primary regular of Ca.
Describe the process where hypomagnesemia may lead to hypokalemia.
b) what measures should be done with or before the use of potassium supplements to correct hypokalemia?
a) Mg is essential for the proper function of the Na/K pump. In hypokalemia, the body is unable to pump K into the cell–> resulting in the loss of K in the urine.
b) Use of Mg supplementation to correct hypomagesemia. Use of Mg supplementation before or with K supplementation.
Hypomagesemia is associated with:
a) hyperkalemia and hypercalcemia
b) hypokalemia and hypercalcemia
c) hypocalcemia and hypokalemia
d) none of the above
c) hypocalcemia and hypokalemia
What condition usually results in hypermagnesemia?
Individuals with renal failure with increase Mg intake.
Mg is essential in 3 systems
- transmission of neuromuscular activity
- neural transmission within the CNS
- myocardial functioning