Magic Bullets Flashcards

1
Q

Who developed Koch’s work to isolate antitoxins

A

Emil vin Behring

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2
Q

Who set up his own research team

A

Paul ehrlich

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3
Q

Who joined ehrlichs team and when

A

Dr hata in 1909

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4
Q

What did hata and ehrlich discover

A

Slavasan 606 to cure syphilis

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5
Q

Who discovered the second major bullet and when

A

Gerhard domagk in 1932

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6
Q

What was the sending magic bulle

A

Prontosil to treat blood poisoning

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7
Q

How did science and technology contribute to discovery

A

Ehrlich was part of Koch’s team and had experience of chemical cures for disease
Technological developments in 19th century made it possible to mass produce pills which made he pharmaceutical industry grow rapidly

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8
Q

How did the government contribute to the discovery

A

After Pasteur and kicks discovery they became more involved

Ehrlich could only carry out research due to government funds

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9
Q

How did individuals contribute to findings

A

Paul ehrlich
Emil Von Behring
Dr hata
Gerhad domagk

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10
Q

Who was Alexander Fleming

A

A chemist

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11
Q

What did Fleming find

A

Bacteria growing and unknown mould was killing it in the same dish which led to him discovering it was penecillin

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12
Q

When did Fleming publish his findings

A

1929 but he was unable to get funding

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13
Q

Who helped Fleming

A

Florey and chain read about his work and in 1939 they set up a team to develop penecillin

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14
Q

What did they text penecillin on

A

Nice in 1949 and in 1941 they tried it on patients

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15
Q

Why were patients still dying

A

There was only a small amount available

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16
Q

When was the large scale production for penecillin

A

1944

17
Q

Why did Florey and Norman heatley go to USA

A

To se did any drug companies would fund their research and ythey we’re finally successful in 1941

18
Q

Impact of penecillin

A

First antibiotic

Helped treat infection in Second World War

19
Q

What was a limitation to penecillin

A

Expensive
Joseph Lister discovered it in 1871 butt didn’t realise it’s potential
Wasn’t enough to treat patients successfully at first

20
Q

Impact of magic bullets

A

Scientific methods showed research worked

They had knowledge of chemical that could treat a particular disease

21
Q

Limitations of magic bullets

A

Could only kill 1 infection

Penecillin was better as it could kill s range of infections at once