Macromolecules Flashcards

1
Q
Cellulose belong to which one of the following macromolecules?
A)Lipids
B)Carbohydrates
C)Proteins
D)Nucleic Acids
A

B) Carbohydrates

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2
Q
What structural level is represented by the coiling of the protein chain backbone into an alpha-helix?
A)Primary Structure
B)Secondary Structure
C)Tertiary Structure
D) Quaternary Structure
A

B) Secondary Structure

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3
Q

Sucrose is a ______.

A

Disaccharide

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4
Q

Which of the following is incorrectly matched?

A)amino acid; protein
B)monosaccharide; carbohydrate
C)nucleotide; nucleic acid
D)glucose; lipids

A

D) glucose; Lipids

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5
Q

What is the primary structure of protein?

A

It is important for determining the secondary and tertiary structure of a protein; it is the sequence of amino acids from one end of protein to another; it is the linear sequence of amino acids that are linked together by peptide bonds

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6
Q

The genetic information is coded in DNA by the ______.

A

Sequence of the nucleotides

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7
Q

T or F:

Water is added to join the monomers of macromolecules.

A

False, water is dehydrated or condensed.

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8
Q
All of the following are examples of biological macromolecules except?
A)Glycogen
B)Cellulose
C)Amino Acid
D)Starch
A

C) Amino Acid

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9
Q
Which of the following is not a structural polysaccharide?
A)Cellulose
B)Chitin
C)Glycogen
D)All are polysaccharides
A

C) Glycogen

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10
Q

T or F:

Phospholipids are amphipathic.

A

True

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11
Q
Amino acids joining together to make a peptide by:
A)Peptide Bond
B)Ionic Bond
C)Covalent Bond
D)Two of the above
A

D)Two of the above

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12
Q
Which one of the following is not one of the six classes of lipids?
A)Pectins
B)Steroids
C)Terpenes
D)Triacyglycerol
A

A)Pectins

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13
Q
Which of the following is not characteristic of DNA?
A)Contains deoxyribose
B)Contains ribose
C)Double stranded
D)Found in the nucleus
A

B)Contains ribose

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14
Q
Which of the following is not a polymer of numerous monomer units?
A)Proteins
B)Lipids
C)Nucleic Acids
D)Carbohydrates
A

B)Lipids

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15
Q
Nucleotides to nucleic acids are as amino acids are to?
A)Proteins
B)Fats
C)Carbohydrates
D)Tryglycerides
A

A)Proteins

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16
Q

Carbohydrates and proteins are built up from their basic building blocks by the ______
A)Addition of a water molecule between each two units
B)Addition of a carbon atom between each two units
C)Removal of a water molecule between each two units
D)Removal of a carbon atom between each two units

A

C)Removal of a water molecule between each two units

17
Q
The single most abundant protein in the body is
A)DNA
B)Hemoglobin
C)Collagen
D)Glucose
A

C)Collagen

18
Q

List the 4 types of Macromolecules

A

Proteins (amino acids), Nucleic Acids (nucleotides), Polysaccharides (simple sugars), Lipids (diverse class)

19
Q

Describe the Macromolecule synthesis process

A

Stepwise from the smaller units. Each addition releases a hydrogen in a process called condensation or dehydration. Must have a reactive hydrogen and reactive OH on each molecule

20
Q

Structure of amino acid protein

A

Carbon atom (chiral center) bonded to a hydrogen atom plus an amino group, carboxyl group, and an R group

21
Q

What type of covalent bond links amino acids?

A

Peptide bonds

22
Q

What are two features of a peptide bond?

A

Particularly strong(resemble double bonds); resists rotation and provides rigid peptide backbone

23
Q

Process of protein synthesis is called _____

A

Translation

24
Q

Define monomeric and multimeric

A

single polypeptides vs multiple polypeptides

25
Which structure can be used to predict higher level protein structures?
Primary structures (linear sequence of amino acids)
26
What are the two shapes of Secondary Structure, and how are these decided?
Alpha-helix and beta-pleated sheets. Determined by hydrogen bonding within polypeptide
27
What are motifs?
Specific short stretches of secondary structures. May have characteristic functions (catalytic, DNA binding) Ex: hairpin loop, helix-loop-helix
28
What is the overall structure of a mature polypeptide?
Tertiary structure
29
What are protein domains?
Discrete, locally folded units of tertiary structure. Typically 50-350 amino acids long, with regions of a helices and b sheets packed together. Proteins with similar functions share common domains
30
How are tertiary structures determined?
Complex intramolecular interactions. (Covalent bonds, ionic bonds, hydrogen bonds, van der Waals interactions, hydroPHOBIC interactions)
31
What is quaternary structure and how is it determined?
Interaction of multiple polypeptide subunits to form multimeric protein. Determined by multiple type of INTERmolecular interactions
32
What are two ways quaternary structure is used?
Cytoskeletal adhesion, regulation (catalytic, cellular signaling, immunological)