Macrocytic Anaemia Flashcards
1
Q
What is macrocytic anaemia
A
low haemogobin with large mean cell volume
2 Types:
- Megaloblastic (B12/ folate deficiency)
- Non-megaloblastic
2
Q
what are the 2 types of macrocytic anaemia
A
Megaloblastic- B12 / folate deficiency
Non-megaloblastic- alcohol, liver disease, myelodisplasia
3
Q
what is pernicious anaemia
A
type of megaloblastic anaemia
autoimmune condition where intrinsic factor isnt made in the stomach which stops the body from being able to absorb B12
4
Q
how does macrocytic anaemia present
A
- fatigue
- brittle nails (onychoschizia)
- loss of appetite/ weight
- palpitations
- pale skin, lips, eyelids
- SOB
5
Q
how do you invesitgate macrocytic anaemia
A
FBC:
- low Hb
- high MCV >95
- often low folate and B12
6
Q
how do you manage macrocytic anaemia
A
B12 and folate Injections
Diet modifications if deficiency
Supplements
7
Q
what are the complications of of macrocytic anaemia if left untreated
A
heart failure
circulatory problems
peripheral neuropathy
dementia
