M6C20 - Patterns of inheritance and variation Flashcards

1
Q

What is discontinuous variation?

A

A type of variation where traits can be assigned to specific categories and is unaffected by environment, such as shoe size or blood type.
-Distinct categories
-Tends to be qualitative

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2
Q

What is continuous variation?

A

A type of variation where traits differ quantitatively and can be influenced by the environment, such as height or weight.
-No distinct categories

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3
Q

What is an example of an environmental factor that can influence variation in animals?

A

Diet

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4
Q

What is an example of an environmental factor that can influence variation in plants?

A

Lack of light which leads to etiolation - This is when plants grow long, pale and unhealthy and are susceptible to disease.

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5
Q

What 2 factors contribute to genetic variation?

A

Meiosis
Random fusion of gametes in fertilisation

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6
Q

How is genetic variation achieved during mitosis?

A

-Crossing over of non-sister chromatids
-Independent assortment of homologous chromosomes.
-Independent assortment of chromatids
-Independent segregation of chromatids

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7
Q

How does crossing over contribute to genetic variation?

A

It exchanges genetic material between homologous chromosomes, leading to new combinations of alleles.

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8
Q

What is independent assortment in meiosis?

A

The random arrangement of chromosomes during meiosis, creating different combinations of alleles.

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9
Q

What is a locus?

A

The specific position of a gene on a chromosome.

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10
Q

Define phenotype.

A

The observable characteristics of an organism resulting from both genotype and environmental factors.

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11
Q

Define genotype.

A

Alleles present within cells of an organism, for a particular trait or characteristic

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12
Q

What is a dominant allele?

A

Only a single allele
is required for the characteristic to
be expressed

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13
Q

What is a recessive allele?

A

The characteristic is only expressed if there is no dominant allele present

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14
Q

What does homozygous mean?

A

Having two identical alleles for a particular gene.

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15
Q

What does heterozygous mean?

A

Having two different alleles for a particular gene.

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16
Q

What is codominance?

A

Where both alleles contribute equally to the phenotype

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17
Q

What is linkage?

A

Different characteristics are located at different loci on the same chromosome and so are inherited together.

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18
Q

What is monogenic inheritence?

A

When a phenotype or trait is controlled by a single gene

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19
Q

What is dihybrid inheritence?

A

The inheritance of two genes at the same time

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20
Q

In dihybrid inheritence, how would the phenotype ratio be different if the genes were autosomally linked?

A

Higher proportion of heterozygous

21
Q

What is sex linkage?

A

When the expression of an allele is dependent on gender due to the gene being located on a sex chromosome.

22
Q

Provide an example of sex-linked inheritance

A

Haemophilia, which is recessive and linked to the X chromosome

23
Q

What is autosomal linkage?

A

When genes are located on the same chromosome (not sex chromosomes) and tend to be inherited together.

24
Q

Explain how autosomal linkage may cause phenotypic ratios to be different from what’s expected:

A

-Both genes occur at the same chromosome.
-No indpendent assortment
-So alleles are inherited together unless crossing over occurs.

25
What is epistasis?
The interaction between genes at different loci, where one gene can mask or modify the expression of another gene.
26
Suggest how one allele inhibits another in epistasis:
-Inhibiting allele codes for a repressor protein -Protein binds to mRNA -Stops transcription
27
What is recessive epistasis?
When a recessive allele at one locus prevents the expression of an allele at another locus, resulting in a 9:3:4 phenotype ratio.
28
What is dominant epistasis?
When a dominant allele at one locus completely masks the alleles at a second locus, resulting in a 12:3:1 phenotype ratio.
29
What is stabilising selection?
Natural selection that favours average stereotypes e.g. babies with average birth weights are more likely to survive than overweight babies.
30
What is directional selection?
Occurs when there is a change in the environment and the normal phenotype is no longer the most advantageous e.g. peppered moths.
31
What is genetic drift?
Change in allele frequency due to the random nature of mutation
32
What is a genetic bottleneck?
When a random event means the size of a population is significantly reduced so therefore the number of alleles in the population also decreases.
33
Why does a genetic bottleneck lead to low genetic diversity?
Many alleles were lost when population dropped. Population is descended from few survivors.
34
What is the founder effect?
When a few individuals of an area colonise a new area, meaning there is a small gene pool for reproduction.
35
What is gene flow?
The movement of alleles between populations
36
What is speciation?
The formation of a new species due to evolution.
37
What is allopatric speciation?
Speciation caused by a physical barrier that isolates populations, leading to different selection pressures and reproductive isolation.
38
Reproductive isolation can occur because
Seasonal changes – individuals develop different flowering or mating seasons, or become sexually active at different times of the year. Mechanical changes – changes in genitalia prevent successful mating. Behavioural changes – a group develops a different courtship ritual that isn’t attractive to the rest of the population.
39
What is sympatric speciation?
Speciation without a physical barrier, often due to chromosomal errors or ecological niches, leading to reproductive isolation.
40
What is artificial selection?
The process where humans select individuals for specific traits to breed, to get desirable characteristics, creating selection pressures.
41
Provide an example of artificial selection.
Dairy cows, where cows with the highest milk yields are bred to increase milk production.
42
What is an example of artificial selection in wheat?
Modern bread wheat, which is hexaploid and was created by hybridizing wild and domesticated wheat species.
43
What are some issues with selective breeding?
Similar genes in generations means: -Some diseases are more dangerous as all the organisms would be affected. -Increased risk of genetic disease caused by -recessive genes. -Inbreeding leads to a reduction in the size of the gene pool, making it more difficult to produce new varieties in the future.
44
What's an ethical consideration for domesticated dogs due to selective breeding?
Dachshund backs and necks have been bred to be longer, and legs have become smaller. They have the highest risk of any breed for intervertebral disc disease which can result in paralysis.
45
What does the Hardy-Weinberg equation predict?
The frequency of alleles in a population and whether allele frequencies are changing over time.
46
What is the Hardy-Weinberg equation?
p + q = 1, where p is the frequency of the dominant allele and q is the frequency of the recessive allele.
47
What does (p + q)² = 1 represent?
The expansion p² + 2pq + q², which gives the frequencies of the three genotypes: p² for homozygous dominant, 2pq for heterozygous, and q² for homozygous recessive.
48
Hardy Weinberg can only be applied to populations which fulfil all of these criteria:
Sexually reproducing organisms Diploid Organisms Large populations Randomly-mating populations No migration into or out of population No mutations occur