M4 - Coagulation Time

Question 1

secondary hemostasis or ___ ?

Answer 1

blood coagulation

Question 2

In ___ or ____, the _____ together with the _____ helps to activate the _____ which will lead to the formation of a ____ in ___, upon action of _____.

Answer 2

secondary hemostasis;
blood coagulation;
intrinsic pathway;
extrinsic pathway;
common pathway;
stable fibrin clot;
vivo;
Factor XIII

Question 3

T/F: The evaluation of the factors involved in the intrinsic and common pathway is important since whether there is deficiency or a higher level than the reference values will have a clinical implication.

Answer 3

T

Question 4

The evaluation of the factors involved in the ____ and _____ is important since whether there is deficiency or a higher level than the reference values will have a ____.

Answer 4

intrinsic;
common pathway;
clinical implication

Question 5

It tests the composite action of all plasma factors acting simultaneously.

Answer 5

Coagulation or clotting time of blood

Question 6

___ or ____ of blood tests the composite action of all ____ acting simultaneously.

Answer 6

Coagulation;
clotting time;
plasma factors

Question 7

The time required for the blood to ____ is a function of the ___ inhibiting ___ on one hand as opposed to the combined factors ____ coagulation on the other hand.

Answer 7

clot;
combined factors;
coagulation;
promoting

Question 8

measure of the ability of the blood to clot and is not influenced by the platelet function besides PF3.

Answer 8

Coagulation time

Question 9

___ is a measure of the ___ of the blood to ___ and is not influenced by the ____ besides PF3.

Answer 9

Coagulation time ;
ability ;
clot ;
platelet function;
PF3

Question 10

The test (coagulation time) measures only the required for the ___ of the ____of ___ sufficient to produce a ___

Answer 10

formation ;
first traces;
thrombin;
visible clot.

Question 11

What are the 2 methods used in Coagulation time?

Answer 11

Capillary Blood Methods
Venous Blood Method

Question 12

What are the two methods/test under the Capillary Blood Methods

Answer 12

Slide Method or Drop
Capillary Tube (Dale and Laidlaw’s Method)

Question 13

In capillary blood methods, coagulation time starts from the _____ of the blood from the ____

Answer 13

first appearance ;
puncture

Question 14

In capillary blood methods, the puncture should be deep enough to ensure ____ in order to ___ the ___ with _____

Answer 14

free flow of blood ;
decrease ;
contamination ;
tissue juice

Question 15

In capillary blood method, slide method is aka?

Answer 15

Drop

Question 16

In capillary blood method, Capillary tube is aka?

Answer 16

Dale and Laidlaw’s Method

Question 17

Slide Method or Drop:

1. Sterilize the ___ or the ___ with cotton moistened with ____. Allow it to __.

Answer 17

finger ;
ear lobe ;
70% alcohol
dry

Question 18

Slide Method or Drop:

2. Make a puncture to a depth of ___. Start the stopwatch as soon as blood ___. ___ the ___ drop of blood with dry cotton.

Answer 18

3mm ;
appears;
Wipe off;
first

Question 19

Slide Method or Drop:

3. Place a ______ of blood on a clean ___.

Answer 19

large drop ;
dry glass slide

Question 20

Slide Method or Drop:

4. After ___, draw a___ or __ through the drop of blood and gently ___ the wire or pin.

Answer 20

3 minutes;
fine wire;
pin ;
lift

Question 21

Slide Method or Drop:

5. Repeat at ____ intervals until tiny strands of __, clings to the ____ or __.

Answer 21

30 second ;
fibrin ;
wire ;
pin

Question 22

Capillary tube is aka

Answer 22

Dale and Laidlaw’s Method

Question 23

Capillary Tube (Dale and Laidlaw’s Method)

1. Sterilize the ___ or the ___ with cotton moistened with ___. Allow it to dry.

Answer 23

finger ;
earlobe ;
70% alcohol

Question 24

Capillary Tube (Dale and Laidlaw’s Method)

2. Make a puncture to a depth of ____. ___ the stopwatch as soon as the blood ___. ___ the ___ drop of blood as soon as blood appears.

Answer 24

3mm;
start ;
appears;
Wipe off;
first

Question 25

Capillary Tube (Dale and Laidlaw’s Method)

3. Place the tube filled by ___ for about ___ of its ____.

Answer 25

capillary action ;
2/3 ;
length

Question 26

Capillary Tube (Dale and Laidlaw’s Method)

4. Lay the ___ on the ___.

Answer 26

tube ;
table

Question 27

Capillary Tube (Dale and Laidlaw’s Method)

5. After ____. Gently break off ___ of the ___.

Answer 27

2 minutes;
1 cm;
filled end

Question 28

Capillary Tube (Dale and Laidlaw’s Method)

6. Repeat at ___ intervals until ___ has occurred. This is revealed by the presence of ___, which span the gap at least ___ between the ____.

Answer 28

30 second;
coagulation ;
strands of fibrin;
5mm;
broken ends

Question 29

What is the reference range for Capillary Blood Methods
(Slide Method or Drop / Capillary Tube )

Answer 29

2-6 minutes

Question 30

What is the method in Venous Blood Method

Answer 30

Lee and White Method

Question 31

What percent of saline solution is used in Lee and White method?

Answer 31

0.85% saline solution

Question 32

Lee and White Method

1. Rinse the ___, ___ and the ___ test tubes with normal saline solution.

Answer 32

sterile syringe;
needle ;
3 ;
normal saline solution.

Question 33

Lee and White Method

2. ___ the test tubes ___, ___, and ___

Answer 33

Number ;
1;
2;
3

Question 34

Lee and White Method

3. Withdraw ____, recording the time of the ____ of ___ in the syringe.

Answer 34

4 cc blood;
first appearance;
blood;
syringe

Question 35

Lee and White Method

4. ___ the needle from the syringe and slowly place ____ of blood in each of the 3 test tubes in order of their number.

Answer 35

Remove ;
1m;

Question 36

Lee and White Method

5. After ____, slowly ____ the ___ and the ____ tubes until ____ has taken place.

Answer 36

3 minutes;
tilt ;
first ;
second ;
coagulation

Question 37

Lee and White Method

6. Test the ___ tube, record the time when tube 3 can be ___ without disturbing the ___.

Answer 37

third ;
inverted ;
clot

Question 38

Lee and White Method

7. ____ from the ___ appearance of blood in the syringe and _____ in the third tube is the ____

Answer 38

Time elapsed;
first ;
clot formation;
coagulation time

Question 39

Reference Range of Lee and White Method

Answer 39

5-10 minutes

Question 40

____ coagulation time is observed in ___, occasionally in diseases like _____, ____, ____, ___, _____

Answer 40

Prolonged ;
haemophilia;

Obstructive jaundice
Anemia
Leukemia
Hemorrhagic disease of the newborn
Onset if severe acute fever.

Question 41

Decreased coagulation time is seen in ___

Answer 41

digitalis medication