M2 Flashcards
The nurse manager on the psychiatric unit was explaining to the new staff the differences between typical and atypical antipsychotics. The nurse correctly states that atypical antipsychotics:
a. Remain in the system longer
b. Act more quickly to reduce delusions
c. Produce fewer extrapyramidal effects
d. Are risk free for neuroleptic malignant syndrome (NMS)
C
(Atypical antipsychotics produce less D2 blockade; thus movement disorders are less of a problem. No evidence suggests that the medication remains in the system longer nor that it acts more quickly to reduce delusions. The atypicals are not risk free for NMS.)
The nurse would assess for neuroleptic malignant syndrome (NMS) if a patient on haloperidol (Haldol) develops a:
a. 30 mm Hg decrease in blood pressure reading
b. Respiratory rate of 24 respirations per minute
c. Temperature reading of 104 F
d. Pulse rate of 70 beats per minute
C
(Increased temperature is the cardinal sign of NMS. This BP is not a significant feature of NMS. There are no significant findings to support the options related to respirations or pulse rate.)
A patient taking fluphenazine (Prolixin) complains of dry mouth and blurred vision. What would the nurse assess as the likely cause of these symptoms?
a. Decreased dopamine at receptor sites
b. Blockade of histamine
c. Cholinergic blockade
d. Adrenergic blocking
C
(Fluphenazine administration produces blockade of cholinergic receptors giving rise to anticholinergic effects, such as dry mouth, blurred vision, and constipation.)
Which behavior displayed by a patient receiving a typical antipsychotic medication would be assessed as displaying behaviors characteristic of tardive dyskinesia (TD)?
a. Grimacing and lip smacking
b. Falling asleep in the chair and refusing to eat lunch
c. Experiencing muscle rigidity and tremors
d. Having excessive salivation and drooling
A
(TD manifests as abnormal movements of voluntary muscle groups after a prolonged period of dopamine blockade. Movements may affect any muscle group, but muscles of the face, mouth, tongue, and digits are commonly affected. Falling asleep is reflective of the sedative effect of these medications. Muscle rigidity and drooling reflect EPS caused from imbalance between dopamine and acetylcholine.)
When the nurse realizes that a patient diagnosed with schizophrenia is not taking the prescribed oral haloperidol (Haldol), which intervention would promote medication compliance?
a. Instructing the patient to have friends monitor his medications
b. Beginning administration of haloperidol (Haldol) decanoate
c. Writing instructions in detail for the patient to follow
d. Changing haloperidol to an atypical antipsychotic
B
(Haloperidol decanoate is a depot medication, given intramuscularly every 2 to 4 weeks. It is unknown whether the patient has a support system. The patient probably received education, including written instructions prior to discharge. Changing to another classification of medication would not necessarily improve compliance.)
When asked how tricyclic antidepressants affect neurotransmitter activity, the nurse should respond that they:
a. Decrease available dopamine.
b. Increase availability of norepinephrine and serotonin.
c. Make available increased amounts of monoamine oxidase.
d. Increase the effects of the chemical gamma-aminobutyric acid.
B
(Tricyclic antidepressants block neurotransmitter uptake, increasing the amounts of norepinephrine and serotonin available. Decreasing dopamine is the action of typical antipsychotic medication. Increasing monoamine oxidase is not the action of tricyclics. Benzodiazepines, not tricyclics, increase the effects of GABA.)
A severely depressed patient has been prescribed clomipramine (Anafranil). For which medication side effects should the patient be monitored?
a. Excess salivation and drooling
b. Muscle rigidity and restlessness
c. Polyuria and coarse hand tremors
d. Orthostatic hypotension and constipation
D
(Alpha1 blockade produces orthostatic hypotension, and cholinergic blockade produces constipation. Mild tremors and urinary retention may occur. Drooling and excessive salvation may occur with SSRIs. Muscle rigidity and restlessness may occur with antipsychotics.)
Which of these statements made by a patient taking the MAOI phenelzine (Nardil) would warrant further instruction?
a. I often forget to wear sunscreen when I go outside.
b. I need to restrict the amount of sodium in my diet.
c. I should not use over-the-counter cold medications.
d. I usually order liver and onions when my wife and I eat out.
D
(MAOIs require patients to observe a tyramine-free diet to prevent hypertensive crisis. Liver is a food that contains large amounts of tyramine. The remaining options have no relevance for MAOI therapy.)
Which patient complaint should receive priority from a patient who is taking the MAOI tranylcypromine (Parnate)?
a. I haven’t had a bowel movement in 2 days.
b. Will you take my temperature? I feel too warm.
c. I get a headache when I drank several cups of coffee.
d. My legs get stiff when I sit in the chair for any length of time.
C
(Hypertensive crisis may occur if a patient taking a MAOI ingests certain food containing tyramine or drugs that cause blood pressure (BP) elevation. Headache is a warning sign of hypertensive crisis. The nurse should assess BP and inquire about other symptoms of hypertensive crisis. Stiffness is not related to MAOI therapy. Elevated temperature is not an initial sign of hypertensive crisis. Constipation is not a sign of hypertensive crisis.)
Sertraline (Zoloft) has been prescribed for a patient with symptoms of a major depression. Which factor was probably most important in the physicians decision to use an SSRI?
a. Good side-effect profile
b. Less expense for the patient
c. Increase in medication compliance
d. Rapid rate of absorption from the GI tract
A
(Compared to other antidepressant medication groups, SSRIs have the best side-effect profile. SSRIs are more costly. No studies have shown that SSRIs result in better compliance. These drugs are absorbed slowly from the GI tract.)
Which statement made by a patient who will be maintained on lithium following discharge will require further instruction by the nurse?
a. I will have my blood work done regularly.
b. When I get home, I may go on a salt-free diet.
c. I have learned not to restrict my intake of water.
d. I understand some people gain weight on lithium.
B
(This statement shows that the patient does not understand the relationship between lithium and sodium. The patient must be taught that changing dietary salt intake will affect lithium levels. Adding salt can cause lower levels; reducing salt can result in toxicity. The remaining options reflect correct information regarding lithium therapy.)
To educate a patient regarding what to expect following the administration of a benzodiazepine, the nurse must understand that benzodiazepines:
a. Have a rapid onset of peak action
b. Reduce availability of GABA
c. Generally diminish the activity of GABA
d. Interact with serotonin to increase availability
A
(Benzodiazepines do have a more rapid onset. There is no effect on the availability or function of GABA. Benzodiazepines do not diminish GABA activity; they enhance it.)
A patient prescribed alprazolam (Xanax) for symptoms of anxiety shares with the nurse that, Im concerned about getting off this medication. Upon which fact will the nurse base the response to the patients concern?
a. Long elimination half-life will result in a manageable withdrawal treatment plan.
b. Rapid absorption and distribution to brain cells make withdrawal more difficult to manage.
c. Sensitivity of the mesencephalic reticular activating system makes addiction unlikely.
d. The combination of medication with an antidepressant often positively impacts withdrawal.
B
(In general, shorter-acting benzodiazepines are more difficult to taper and potentially cause more problems with withdrawal. The remaining options are neither true nor relevant.)
Which patient outcomes would be most applicable for the patient who has been taking benzodiazepines? Patient will state:
a. That there are specific foods to avoid while on this medication
b. An understanding of how to increase medication dosage
c. That alcohol is a substance to avoid while on the medication
d. An understanding that he or she can return to work while on this medication
C
(Combining a benzodiazepine with alcohol or other CNS depressant is potentially fatal. No food restrictions exist. Dosage should not be changed without consultation with the physician. Patients may return to work unless experiencing sedation. In this case, they would be cautioned not to operate machinery.)
Which person with mania is the least likely candidate to receive lithium? The patient who is:
a. Six weeks pregnant
b. Recovering from a hysterectomy
c. Taking hormone replacement therapy
d. Displaying symptoms of postpartum depression
A
(Lithium is contraindicated during pregnancy because of teratogenic effects. The remaining options would not be contraindicative to lithium therapy.)
An individual with poststroke depression is receiving an SSRI. What is the rationale for giving the medication at breakfast and again at midday?
a. Prevent insomnia
b. Prevent toxic reactions
c. Decrease afternoon sleepiness
d. Give an opportunity to monitor behavior closely
A
(CNS stimulants may cause insomnia if given late in the day. Toxicity is a result of excessive medication in the system, not when it is administered. The drowsiness resulting from SSRI use would not be minimized if taken as described. There is no expectation that resulting behaviors will need to be so closely monitored.)
A patient who has received lithium for 3 weeks to control acute mania has the following symptoms: coarse hand tremor, diarrhea, vomiting, lethargy, and mild confusion. The priority nursing action should be to:
a. Administer prn Cogentin to relieve the symptoms.
b. Provide reassurance that the symptoms are transient.
c. Obtain a stat lithium level; hold lithium pending results.
d. Assist the patient to decrease the sodium in their daily diet
C
(The symptoms the patient is experiencing are consistent with moderate lithium toxicity. The nurse should hold lithium, obtain a stat lithium level, and notify the physician. Cogentin is inappropriate; the symptoms are not EPS. The nurse may reassure the patient but cannot suggest that the symptoms will resolve over time. Minimizing salt would worsen lithium toxicity.)
A patient with rapid cycling bipolar disorder is not responding well to lithium. The patient tells the nurse, It feels as though Ill never get well. I get better, and then I get worse. The reply that is based on knowledge of current therapy would be:
a. You’re feeling very discouraged aren’t you?
b. Its not all bad, is it? Sometimes you like being high.
c. Another drug, valproic acid, is proving effective for rapid cycling.
d. If your kidneys hold out, the lithium will eventually control the symptoms.
C
(Valproic acid is a first-line agent for the treatment of bipolar disorder. It is particularly effective with rapid cycling. The other options are not responsive to the question stem, which asks for knowledge of current therapy.)
Which statement by a patient with generalized anxiety disorder for whom lorazepam (Ativan) is prescribed as needed (prn) suggests the patient understands the purpose of the medication?
a. I can talk with my therapist more easily after my medication takes effect.
b. I wonder if I will have to take this medication for the rest of my entire life.
c. I’m embarrassed and don’t want anyone to know I’m on this kind of medication.
d. I’m going to ask for my prn dose so I can sleep instead of worrying about my kids.
A
(The patient recognizes the therapeutic effects of the medication in assisting her to work effectively with the therapist. The remaining options show questions and inappropriate use of the medication.)
A patient has been taking chlorpromazine (Thorazine) for the past 2 weeks. He drools, has hand tremors, and walks with a shuffling gait. The nurse would correctly attribute these behaviors to:
a. Akinesia
b. Tardive dyskinesia
c. Pseudoparkinsonism
d. Neuroleptic malignant syndrome
C
(These are symptoms of pseudoparkinsonism associated with dopamine blockade. Tardive dyskinesia occurs after long-term therapy. The remaining options are not associated with the symptoms mentioned.)
What intervention will the nurse request for a patient reporting gastrointestinal side effects related to valproate therapy?
a. Mild laxative
b. Low-fat diet
c. Oral antacid
d. Histamine-2 antagonist
D
(Indigestion, heartburn, and nausea are common side effects of valproate therapy. The administration of a histamine-2 antagonist such as famotidine (Pepcid) is sometimes helpful. The other options would have no impact on the complaint.)
A patients serum lithium level is reported as 1.9 mEq/L. The nurse should immediately:
a. Restrict sodium and fluid intake.
b. Assess for signs and symptoms of toxicity.
c. Seek to have the patient transferred to ICU.
d. Notify the patients physician immediately.
B
(A serum lithium level this high suggests that the patient may be experiencing symptoms of lithium toxicity. Clinical assessment is essential to determine what, if any, signs and symptoms are present. After the clinical assessment has been made, the nurse can provide the physician with a complete picture. Restricting sodium and fluids would raise the serum level. Transferring may not be necessary and would require a physicians order.)
To evaluate outcomes for a patient with schizophrenia receiving typical antipsychotic drug therapy, the nurse would look for improvement in:
a. Affective mobility
b. Positive symptoms
c. Self-care activities
d. Cognitive functioning
B
(Typical antipsychotic medications produce improvement in the positive symptoms of schizophrenia such as hallucinations and delusions. Negative symptoms and cognitive functioning tend to show less improvement.)
During a psychiatric emergency, IM ziprasidone (Geodon) is administered to an assaultive patient. During the next 2 hours, it is of primary importance that the nurse assess for:
a. Tardive dyskinesia
b. Anticholinergic effects
c. Orthostatic hypotension
d. Pseudoparkinsonism
C
(The side effect most likely to appear is orthostatic hypotension related to alpha1 receptor blockade preventing peripheral blood vessels from automatically responding to positional change. Anticholinergic effects are of lesser concern. The remaining options are less likely to occur at this point in therapy.)