M1: immune system and antigens Flashcards
define immunity
being resistant to infection
phagocytosis
cells eat other cells
adaptive immunity
A type of resistance characterized by
specificity for each individual pathogen, or
microbial agent, and the ability to remember
a prior exposure
innate immunity
natural immunity
no memory, nonspecific
antigen
foreign substances that induce an immune response
-on rbc
antibodies
in plasma/serum
cells of the innate system
neutrophils, eosinophils, basophils, monocytes, lymphocytes
neutrophil function
first responder to infection; phagocytosis
eosinophil function
kill parasites
basophil function
induce and maintain allergic reactions
monocyte function
phagocytosis
tissue cells
macrophages, mast cells, dendritic cells
macrophages function
phagocytosis
mast cell function
playa role in allergic reactions
the ability to remember
a prior exposure
dendritic cell
the most potent phagocytic cell and most effective antigen presenting cell
cells of the adaptive system
lymphocytes: B cells, T cells, NK cells
B cells function
produce antibodies
t cells function
produce cytokines to contribute to immunity by stimulating b cells to product antibodies
NK cells (natural killer)
kill target cells without any prior exposure
organs of the immune system
bone marrow, thymus, spleen, lymoph nodes
bone marrow function
maturation of b and nk cells
thymus function
maturation of t cells
spleen
filters blood
lymph nodes
place where t cells, b cells and antigens occurs
explain how some antigens are immunogens
some antigens are too small or too difficult to bind to be detected by the immune system
discuss the features of antigens that determines immunogenicity
size-the bigger the better
foreignness- the more different the better
dosage- the more, the better
route of admin.- in through the skin is better than on the skin
haptens
a nonimmunogenic must combine with a carrier to become larger so it can stimulate a response
