M1: Fluids & Electrolytes Flashcards
TBW: 60%
Water
Four compartments of Human body
Water, Protein, Fat & Bone ash
Example of transcellular
CSF, Synovial & Ocular
Total Body Water: of TBW
50-70%
Total Body Water: young adult male
60%
Total Body Water: young adult female
50%
Total Body Water: decrease with
Aging
Total Body Water: increase with
Newborn
Total Body Water: three functional compartments
Plasma, Interstitial fluid & Intracellular volume
ECF is composed
Plasma & Interstitial Fluid
Major cation in the ECF
Na
Major cation in the ICF
K
Major anion in the ECF
Chloride
Major anion in the ICF
Phosphate & Proteins
Plasma volume 5%, interstitial 15%.
ECF
Total number of osmotically active particles
Osmotic pressure
Serum Osmolality by giving value of
Na, Glucose & Ures
Normal exchange of F&E
Water exchange & Salt gain and losses
Normal individual water consumed
2-2.5 L
H20 Losses: stool
250cc
H20 Losses: urine
800-1500cc
H20 Losses: insensible
600cc
Irreversible brain damage. Hypoxic Encephalopathy.
6minutes
Classification of body fluid changes
Volume, Concentration & Composition
Classic for Volume Excess. Distenden neck veins, Increase CVP & Murmur.
CHF
Normal Atrial pressure
8-15mmHg
Increase in BUN & Crea
Azotemia
Daily salt intake
50-90 mEq
Salt gain & losses is maintained by
Kidney
Baroreceptors found in the
Carotid
Osmoreceptors found in the
Kidney
Most common fluid disorder in a surgical patient. Most common ECF loss GI fluids
Volume deficit
Iatrogenic, renal insufficiency, cirrhosis and CHF
Volume excess
Common CNS manifestation in Hyponatremia
Seizure & coma
For every 100mg/dL increment in plasma glucose above normal, the plasma sodium decreased by 1
Check glucose for hyponatremia
Common cause of hypernatremia
Iatrogenic sodium administration
Whether high or low sodium this manifestation will occur
Seizure
Electrolyte composition
Potassium, Calcium, Phosphorus & Magnesium
Excessive K intake. Increased release of K from cells. Impaired K excretion by kidneys. Seen in high voltage electrical burn.
Hyperkalemia
Needed for depolarization
Potassium
When severely dehydrated you become
Acidotic
Frequent drug offender that causes hypokalemia
Furosemide
Usual manifestation of Hypokalemia in NMS
Weakness & Paralysis
Contained in bone matrix. Protein bound 40%, completed to phosphate plus anion 10%.
Calcium
Normal calcium level
8.5-10.5 mEq/L
Bony mets, primary hyperparathyroidism & secretion of parathyroid hormone related protein.
Hypercalcemia
Looks like catatonia
Hypercalcemia
Below 8.5mEq/L. Etiology is pancreatitis, severe soft tissue infections, renal Failure & etc.
Hypocalcemia
Adjust total serum calcium down by _______ for every 1g/dL decrease in albumin.
0.8mg/dL
Decreased urinary excretion, increased intake and endogenous immobilization.
Hyperphosphatemia
Decreased intake. Intracellular shift. Increased excretion.
Hypophosphatemia
50% incorporated in bone. Excreted in feces & urine. Kidneys conserve this. Essential for proper functioning if enzyme system.
Magnesium
Severe renal insufficiency. Parallel changes in K excretion. Excess antacid intake.
Hypermagnesemia
Water constitutes how many percent of TBW
50-60%