m1 chave Flashcards
This theory states that all blood cells are derived from a single progenitor cell called pluripotent stem cell.
a. Unitarian theory
b. Dualistic theory
c. Stem cell theory
-Unitarian theory
The renewal or differentiation of HSC’s is determined by the microenvironment in the bone marrow.
a. Dualistic model
b. Instructive model
c. Stochastic model
-instructive model
What objective is used to view metastatic tumor cells or lymphoblasts?
a. HPO
b. OIO
c. LPO
-LPO
The center of leukopoiesis
a. Reticular adventitial cells
b. Fat cells
c. Bone marrow
-Reticular adventitial cells
Which is the preferred site of bone marrow collection if the patient can only lie supine.
a. Sternum
b. Posterior superior iliac crest of the pelvis
c. Anterior superior iliac crest of the pelvis
-Anterior superior iliac crest of the pelvis
Precursor cell of erythrocyte
a. Histiocyte
b. Reticular cells
c. Normoblast
-Normoblast
A profound defect in the maturation of all formed elements is known as _____
a. Homoplastic hematopoiesis
b. Heteroplastic hematopoiesis
c. Dyspoiesis
c. Dyspoiesis
Bone Marrow aspirate can be used for histopathology if properly preserved in _____.
a. EDTA
b. 10% formalin
c. 22% albumin
-10% formalin
It is the standard strain used for core biopsy specimens.
a. H&E stain
b. Prussian blue
c. Wright’s stain
a. H&E stain
It is a group of specific glycoproteins that regulates the proliferation, differentiation and maturation of hematopoietic precursor cells.
a. HLA-DR
b. HSC’s
c. Cytokines
c. Cytokines
Major site of T cell production
a. Liver
b. Thymus
c. Kidney
d. Spleen
-Thymus
It is the largest hematopoietic cell found in a normal bone marrow aspirate
a. Megakaryocyte
b. Myeloblast
c. Osteoblast
a. Megakaryocyte
This theory states that all blood cells are derived from a single progenitor cell called pluripotent stem cell
a. Unitarian theory
b. Dualistic theory
c. Stem cell theory
-Unitarian theory
This theory states that each of the blood cell lineages is derived from its own stem cell
a. Monophyletic Theory
b. Dualistic Theory
c. Unitarian Theory
-Dualistic Theory
Bone marrow can produce ____ of cells/kg of body weight each day.a
a. 6 billion
b. 2.5 billion
c. 1.5 billion
-6 billion
It is known as the center of Erythropoiesis
a. Macrophage
b. Bone Marrow
c. Mast Cells
a. Macrophage
Bone marrow aspirate should be examined under LPO to assess all of the following excep,
a. Observe fat to marrow ratio
b. Computation of M:E ratio
c. Estimation of Megakaryocytes
d. Search for tumor cells in cluster
b. Computation of M:E ratio
_____ is added to the solution to reduce the occurrence of basket or smudge cells to the bone marrow specimens.
a. 10% formalin
b. 22% Albumin
c. EDTA
b. 22% Albumin
Which of the following stromal cells in the bone marrow secretes cytokines and is also involved in the regulation of marrow volume?
a. Mast Cells
b. Endothelial Cells
c. Adipocytes
c. Adipocytes
Which of the following developmental period of hematopoiesis occurs at the 19th day after fertilization?
a. Mesenchymal Period
b. Hepatic Period
c. Myeloid Period
-Mesenchymal Period
Which cells are produced by the kidney and spleen during the Hepatic period?
a. Erythroblast
b. T cell
c. B cell
-B cell
What is the normal Myeloid to Erythroid (M:E) ratio range in normal range adult?
a. 5.1:1-6.2:1
b. 1.5:1-3.3:1
c. 2.1:1-3.5:1
-1.5:1-3.3:1
It is the bone forming cells
a. Osteoblast
b. Osteoclast
c. Mast Cells
-Osteoblast
If the bone marrow has few or no hematopoietic cells it is known as ____
a. Aplastic
b. Hypoplastic
c. Dry Tap
-Aplastic
