M1

Question 1

True or False
Blood supply from the portal vein and hepatic artery merges into the central canal and flows into the sinusoidal spaces from the liver to other parts of the body.

Answer 1

-FALSE
(Hepatic Artery merges into the sinusoidal and flows into the central canal).

Question 2

Reference value for unconjugated bilirubin (SI UNIT)?

Answer 2

-3 - 14 umol/L

Question 3

A condition that most often results from the retention of bilirubin, wherein a yellowish discoloration of the skin would only appear when the level of the total bilirubin is between 3.0 - 5.0 mg/dL?

Answer 3

-Overt Jaundice

Question 4

Bilirubin fraction that is expected to elevate in condition such as hemolytic anemia

Answer 4

-Unconjugated Bilirubin

Question 5

What are the 2 fractions of bilirubin?

Answer 5

✔ Unconjugated Bilirubin
✔ Conjugated Bilirubin

Question 6

A test which is considered a sensitive and specific marker for hepatic and posthepatic jaundice?

Answer 6

-Conjugated Bilirubin

Question 7

A specific identity as for the reason why there is NO esterification of urobilinogen in Type 1 Crigler Najjar?

Answer 7

-Complete Abscenes

Question 8

Other Name of Jaundice?

Answer 8

-Icterus

Question 9

Other Name of Jaundice?

Answer 9

-Hyperbilirubinemia

Question 10

An immediate precursor of the substance that is responsible for giving brown color to the feces?

Answer 10

-Urobilinogen

Question 11

Which of the following statements is true?

a. Bilirubin is too large to be —-because it is bound to a carbohydrate called albumin
b. Cholestatic jaundice is caused by the impaired uptake of bilirubin in the liver
c. Doblin-Johnson syndrome is characterized by an intense dark pigmentation in the gallbladder
d. Rotor syndrome is due to a decrease concentration or activity ligandine

Answer 11

-D. Rotor syndrome is due to a decrease concentration or activity ligandine

Albumin is a PROTEIN
Cholestatic Jaundice is a Post Hepatic it should be Retention Jaundice a Pre Hepatic
A intense dark pigmentation in the LIVER

Question 12

Which of the following is characteristic of a jaundice caused by excessive lysis of erythrocytes?

a. Increase unconjugated bilirubin
b. Positive urine bilirubin
c. Darkly Colored Stool
d. Disposition of the bilirubin in the brain

Answer 12

-A
-C
-D

Question 13

What is expected in the level of UPDGT in Gilbert’s Syndrome?

Answer 13

-Decrease

Deficiency in the genetic mutation in the gene UGT1A1

Question 14

Which of the following statements are correct?

a. Majority of urobilinogen is formed in the oxidation to urobilin is converted to be majority of total

Answer 14

-B
-D

Question 15

What is expected in the levels of the following analytes in biliary obstruction?

-Total Bilirubin:
-Conjugated Bilirubin:

Answer 15

-Total Bilirubin: Increase
-Conjugated Bilirubin: Increase