Lytes Flashcards
Rx of hypermagn when cardiac toxicity present
Calcium bc mg is blocking the calcium
Hypermagnesemia symptoms
Nause vomiting ileus Depressed reflexes Decrease parasympathetic tone dilated pupils Paralysis apnea resp depression Bradycardia pR and QT prolongation Hypotension VFib and bradycardia arrest
Rta with high urine pH
Autoimmune diseases
Ampho, lithium, ifosfamide
Nephrocalcinosis
Type I distal
Requires 5-15 mEq/kg/day
Fanconi is what type of RTA
Proximal type II
Lupus associates RTA
Type IV
Also type I with high K
Renal loss of magnesium
What drugs
Amino glycosides Ampho Cisplatin Pentamidine CSA Egf antibodies Loop and thiazides
Type of RTA associated with ifos
Type I distal RTA
Or type II !!!!
RTA associated w sjogrens
Type I RTA.
Needle shaped crystals
Substance abuse
Low K
Positive uag
Hippurate intoxication from glue sniffing
Hippurate crystals are needle shaped
Hippurate acts as non re absorbable anion in CCD causing hypokalemia
Hypokalemic metaboli alkalosis
Hypertension
Family history
Liddle’s syndrome
Mutation in Liddle’s
Carboxyl tail of either b or y subunit of eNac
Urinary calcium in gitelman’s
Low urinary calcium/cr <0.1mg/mg
Increased urinary K CL Na
Batters urinary electrolytes
Urinary ca/cr >0.4mg/mg
Increases in Na K Cl
Licorice
Hypokalemic metabolic alkalosis and hypertension
Inhibits 11b OHsteroid dehydrogenase type II allowing cortisol to act as mineralocorticoid
Urinary K Na CL increased
Vomiting
Increased renal k secretion
Due to hco3 acting as a non-reabsorbable ion.
Urine pH will be alkaline as a result of NaHCO3 excretion