Lymphoma

Question 1

lymphoma definition

Answer 1

neoplastic tumour of lymphoid cells (forming discrete mass)

found in lymph nodes bone marrow and or blood

lymphoid organs

skin( t cell disease)

rarely anywhere (cns, testes occular)

200 cases per year

non hodgkins lymphomas 80%

hodgkins lymphoma 20%

Question 2

lympoma associated with H.Pylori

Answer 2

gastric MALT mucosa associated lymphoid tissue, marginal zone NHL of stomach

Question 3

sjorgrens syndrome and coleaics disease lymphomas

Answer 3

sjorgens: marginal zone NHL of parotid lymphoma

gastric MALT ( marginal zone NHL) due to gastric chronic antigen stimulation, indolent condition treat with triple therapy

small bowel T cell lymphoma EATL (enteropathy associated T-cell non hodgkin lymphoma), aggresive mature T-CELL perforation abdo pain, B-SYMPTOMS

also hasmitots thyroiditis –> thyroid MALT lymphoma

Question 4

HTLV1 infection is associated with

Answer 4

adult t cell leukaemia lymphoma

Question 5

CLL vs Small lymphocytic lymphoma

Answer 5

same disease however CLL is primarily bone marrow, SLL is lymph nodes.

diagnosed on routine bloods, lymphcytosis >5 smear cells, low serum Ig