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Oncology > Lymphoma > Flashcards

Lymphoma Flashcards

1
Q

Characterized by reed sternberg or owl eye cells

A

Hodgkins Lymphoma

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2
Q

Chemotherapy regimen for Hodgkins

A

ABVD

Adriamycin Bleomycin Vincristine Dacarbazine

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3
Q

Common side effect of bleomycin

A

Pulmonary toxicity

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4
Q

What infectious agent predisposes to Gastric MALT lymphoma?

A

H pylori

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5
Q

What infectious agent predisposes to multicentric Castlemans disease / primary effusion lymphoma?

A

Human herpesvirus 8 (HHV-8)

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6
Q

What infectious agent predisposes to lymphoplasmacytic lymphoma?

A

Hepatitis C

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7
Q

What infectious agent predisposes to Diffuse large B cell lymphoma and Burkitts or any Hodgkins Lymphoma?

A

HIV

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8
Q

What infectious agent predisposes to adult T cell leukemia/lymphoma?

A

HTLV-1

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9
Q

What infectious agent predisposes to Hodkins Lymphoma

A

EBV

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10
Q

Cytogenetic translocation in Mantle cell lymphoma

A

t(11;14)

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11
Q

Cytogenetic translocation in follicular lymphoma

A

t(14;18)

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12
Q

Cytogenetic translocation in anaplastic lymphoma

A

t(2;5)

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13
Q

Cytogenetic translocation in burkitts lymphoma

A

t(8;14)

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14
Q

Smudge or basket cells

A

B cell CLL / small lymphocytic lymphoma

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15
Q

CD5 Positive lymphomas are:

A

Mantle cell lymphoma
B cell CLL
Lymphoplasmacytic lymphoma

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16
Q

Most common treatment of B cell CLL

A

Chlorambucil or Fludarabine / Bendamustine

17
Q

CD5 Negative lymphomas

A

MALT lymphoma

18
Q

Treatment of MALT?

A

Single agent chlorambucil

Eradication of H pylori

19
Q

Most common presentation of mantle cell lymphoma

A

Palpable lymphadenopathy

Lymphomatosis polyposis in the large intestines with Waldeyer ring involvement

20
Q

Treatment of Mantle cell lymphoma?

A

HyperC-VAD
R-HyperC-VAD

Rituximab + Cyclophosphamide Vincristine Doxorubicin Dexamethasone Cytarabine Methotrexate

21
Q

Double hit lymphomas MYC and BCL6

A

Diffuse B cell lymphoma

22
Q

Starry sky appearance

A

Burkitts lymphoma

23
Q

The most rapidly progressing tumor that always needs CSF examination to rule out mets

A

Burkitts lymphoma

24
Q

When should treatment for burkitts start?

A

Treatment for both children and adults should be started within 48 hours of diagnosis
High dose cyclophosphamide

25
Q

Hairy cell leukemia have monocytopenia and are prone to infections to

A

Mycobacterium avium intracellulare

26
Q

Indolent mature T cell lymphoma with eczematous skin lesions

A

Mycosis fungoides

27
Q

Sezary syndrome

A

Mycosis fungoides or cutaneous T cell lymphoma

28
Q

Tropical spastic paraparesis is a presentation of what lymphoma

A

Adult T cell lymphoma

29
Q

Flower cells

A

Adult T cell lymphoma HTLV 1

30
Q

Has best survival rate among any aggressive lymphoma

A

Anaplastic large T cell lymphoma

31
Q

Treatment of anaplastic T cell lymphoma?

A

Same as any aggressive lymphoma but rituximab is omitted

32
Q

Pattern of fever in Hodgkins lymphoma

A

Pel Ebstein fever

33
Q

Popular chemotherapy regimen for Hodgkins

A

ABVD

Doxo Bleo Vincristine Dacarbazine

34
Q

Electric shock sensation into the lower extremities upon flexion of the neck in patients receiving thoracic radiotherapy

A

Lhermitte’s syndrome

35
Q

Lymphoma-like disorder presenting as bulky lymphadenopathy which is non progressive and self limiting

A

Rosai Dorfman syndrome

Oncology (4 decks)

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