lymphoma

Question 1

define lymphoma

Answer 1

malignant proliferation of lymphocytes which accumulate in lymph nodes

Question 2

2 types pf lymphoma

Answer 2

Hodgkin’s lymphoma

Non Hodgkin’s lymphoma

Question 3

2 ypres of non hodgkin lymphoma

Answer 3

aggressive

indolent

Question 4

compare spreading of hodgkin and non hodgkin’s lymphma

Answer 4

hodgkin - spread continuously, nearby

non hodgkin - spreads non continuously

Question 5

causes of lymphoma

Answer 5

1. primary immunodeficiency
2. secondary immunodeficiency
3. infection
4. autoimmune

Question 6

symptoms of lymphoma

Answer 6

Lymphadenopathy
SVC obstruction
B symptoms
- Weight loss
- Appetite loss
- Night sweats
Fever

Question 7

signs of lymphoma

Answer 7

• painless LN enlargement
• Hepatosplenomegaly – enlargement of liver and spleen
• compression syndromes

Question 8

describe indolent lymphomas

Answer 8

Slow growing and advanced at presentation

•”Incurable”

•Many different sub-types

Question 9

give 3 compression syndromes

Answer 9

Press on iliac vessels in groin 🡪 DVT

Press on spinal cord 🡪 malignant spinal cord compression

Press on vessels in neck 🡪 superior vena cava compression

Question 10

investigations for lymphoma

Answer 10

• FBC
• lymph node biopsy and histology
• PET scan