lymphoid structures Flashcards

1
Q

primary immune organs

A

bone marrow - immune cell production, B cell maturation

Thymus- T cell maturation

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2
Q

secondary immune organs

A

spleen, lymph nodes, tonsils, Peters patches

allows immune cells to interact with antigen

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3
Q

lymph node

A

a secondary lymphoid organ that has many afferents, 1 or more efferents.

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4
Q

lymph node is encapsulated with ____

A

trabecular

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5
Q

function of lymph nodes

A

nonspecific filtration by macrophages, circulation of B and T cells, and immune response activation

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6
Q

lymph node is made of 3 parts

A

follicle, medulla, paracortex,

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7
Q

follicle

A

site of b cell localization and proliferation, in outer cortex. primary follicles are dense and quiescent. secondary foibles hav pale central centers and are active

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8
Q

medulla

A

consists of medullary cords (closely packed lymphocytes and plasma cells) and medullary sinuses. Medullary sinuses communicate with efferent lymphatic and contain reticular cells and macrophages

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9
Q

paracortex

A

contains T cells

region of cortex between follicle and medulla. contains high endothelial venules through which T and B cells enter from blood. Not well developed in patients with digeorge syndrome.

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10
Q

paracortex ____ in an extra cellular immune response

A

enlarges (ex EBV ad other viral infections -> paracortical hyperplasia -> lyphadenopathy)

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