LYMPHEDEMA SYNDROMES Flashcards
1
Q
NONNE-MILROY
congenital lymphedema
1) Incidence
2) Inheritance
3) Features
A
1) F>M
2) AD
FLT4 VEGF
3) Within first 2 years :
3:1 LE:UE
Bilateral
Intestinal lymphangiectasias + Cholestasis
2
Q
MEIGE’S DISEASE
lymphedema praecox
1) Incidence
2) Inheritance
3) Features
A
1) F>M
2) AD
FOXC2
3) lower extremity (L>R)
unilateral in 70%
Associated with vertebral + cerebrovascular anomalies + hearing loss + double row of eyelashes (Distichiasis)
m/c cause of 1o lymphedema
onset 9-25 years old, estrogen may play a role
