Lymphatics Flashcards
1
Q
3 Components of Lymphatic System
A
- lymph fluid
- lymphatic vessels
- organized lymph tissue
2
Q
Embryology
- Mesoderm
- Endoderm
A
- Mesoderm: lymphatic vessels, nodes, spleen
- Endoderm: thymus and part of tonsils
3
Q
Fluid Balance
A
30 L fluid capillary–> interstital space
-90% to capillaries; 10% lymphatic system
4
Q
Nutrition
A
- fat absorbed via chylomicrons
- travel via lacteals–> larger lymph vessels–> thoracic duct–> venous system
- returns proteins to vasculature
5
Q
What tissues do not have lymphatic vessels
A
- epidermis
- endomysium of muscle
- cartilage
- Bone marrow
6
Q
Lymphatic Vessels Route
A
Terminal lymphatics->collecting vessels->afferent lymph vessels->lymph node->efferent lymph vessels->lymphatic trunks->thoracic duct or R lymphatic duct->venous system
7
Q
Terminal Lymphatics
A
- lymph formation starts interstitial space with initial lymphatics
- lined by leaky endothelium and enchored to ECM
- go into collecting vessels
8
Q
Collecting Vessels
A
- have two-leaflet bicuspid valves to prevent retrograde flow
- contains smooth muscle
- autonomic innervation
- afferent prior to lymph node and efferents drain the node
9
Q
Lymph Nodes
A
- superficial and deep
- filtration of lymph fluid
- maturation of lymphocytes
10
Q
Path of Lymph Flow through a Node
A
- Afferent brings lymph to node
- subscapsular space: reticular fiber, dendritic cells initial immune response
- Outer Cortex: B cells
- Deep Cortex: T Cells
- Medullary Sinus: B cells and plasma cells
- Efferent lymph exits through Hilum
11
Q
Lymphatic Trunk
A
Lumbar- drains lymph from lower limb and pelvic organs Intestinal- drains abdomen Bronchomediastinal- drains thorax Subclavian- drains upper limbs Jugular- drains upper head and neck
12
Q
Cisterna Chyli
A
- located at L1-2
- drains lower body
- gives rise to thoracic duct
13
Q
Thoracic Duct
A
- pierces Sibsons fascia twice and empties into L subclavian and L IJV
- Drains L head/neck, L UE, L thorax/abdomen, LL
14
Q
Right Lymphatic Duct
A
- origin from R jugular and subclavian trunk
- terminates at R subclavian R/IJV junction
- Drains R head/neck, R UE, R thorax, heart, lungs
15
Q
Spleen
A
- location: beneath ribs 9-11 on left
- characteristics: largest mass of lymphoid tissue, pressure sensitive
- Functions: destroys damaged RBC, clears bacteria, synthesizes immunoglobulin