Lymphatic System: Danto Flashcards
KCU started in
1916
first described lymphatics as a system
1653: Olaf Rudbeck
(Sweden)
Date: _____ emphasized that diagnosis of the fascia and treatment of the lymphatic system was vital for maintaining health and treating disease
•1874: A. T. Still
______________ (date) published Applied Anatomy of the Lymphatics
1922: Frederic Millard, D.O.,
Lymphatic development begins _______ and is of significant prescense by _________
during 5th week of gestation
signficant prescene by 20 weeks
Where is lymphatic system derived from?
Mesoderm,
but thymus and part of tonsils are endoderm
Lymphatic development
Lymphoid tissue is immature @ birth and increases UNTIL puberty when immine system continues to mature, by lymphoid tissue regresses and levels off
immune system in geriatrics
delines and patients may not mount a fever
3 components of lymphatic system
- organized lymphatic tissue and organs (spleen, liver, thymus, tonsils, appendix, visceral lymphoid tissue, lymph nodes)
- Fluid
- vessels
Fx of lymphatic system
Maintain homeostasis (immune, digestive, fluid balance and waste)
Spleen
Location:
Characteristics:
Functions:
Spleen
Location: L side, below ribs 9-11
Characteristics: spleen is the largest mass of tissue and sensitive to pressure
Functions: destroy damaged/ deformed RBC, make Ig’s, clear bacteria
Moving the diapragm does what?
drives splenic fluid
drives hepatic fluid
LIVER
Location:
Characteristics:
Functions:
Location: RUQ, can palpate at the R costal margin
Characteristics: pressure sensitive
Functions: forms half of bodies lymph, clears bacteria, gatekeeper of hepatobiliary pancreatic venous and lymphatic drainage
Thymus
Location:
Characteristics:
Fx:
Loccated: anterior mediastinum
Characteristics–> large in infancy and peaks at 2yo. After puberty, it is replaced by fatty tissue
Fx: makes T cells in kids and little /no fx in adults
Tonsils
Location:
Characteristics:
Fx:
Location: located in posterior oropharynx: palatine (lateral pharynx-traditional), lingual (posteiror 1/3), pharyngeal (adenoids at nasopharyngeal border)
Characteristics: most are not visible 6-9 monthes, remains englarged through childhook
Fx: allows cells to build immunity early in life, not needed
Appendix
Location
Characterists
Fx
Location–> proximal end of cecum (LI)
Characteristics- has lymphoid pulp; dies with age
Fx- part of the gut-assx lymphoid tissue (GALT)
Visceral lymphoid tissue (gastrointestinal assx lymphoid tissue :GALT))
peyers path, lacteals (lymphatic capillaries of small bowel)
What is lymph fluid?
•Substances that leak out of the arterial capillaries into the interstitiumget taken up by the lymphatic capillaries like fluids, proteins, electrolytes, and cells
•30 L of fluid move from capillaries to interstitial space each day
–90% to capillaries; 10% to lymphatic system
–½ of diffused plasma proteins re-enter system via lymph
•When fluid overload occurs, lymphatic system helps prevent tissue damage by clearing the excess
–“Second/third spacing”
35%-60% of the drainage through the thoracic associated with _________
RESPIRATION
•“pump” effectof the diaphragmatic crura onthe cysternachyli
•Junctures areunder sympathetic control
Restrictions of lymphatic flow must be first drained through the _______________
the assx terminal area
Where does lymph go?
Lymph bathes all tissues.
Some tissue that does not have lymphatic vessels, but uses diffusion are the [epidermis, endomysium, catilage, bone marrow]
Lymph channels begin as what?
Blind endothelial tubes or capillaries made up of 1 layer of leaky squamous epithelium made up of anchoring filaments.
What is the flow of lymphatics?
Lymphatic capillaries–> collecting lymphatics–> afferent lymphatic vessels–> efferent lymphatic vessels–> thoracic duct or R lymphatic duct–> venous system
lymphatics run with veins