lymphatic/immunity Flashcards

1
Q

lymph vessels include:

A

Lymphatic capillaries
lymphatic vessels
lymph nodes
ducts

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2
Q

Primary lymphoid organs

A

red bone marrow

thymus

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3
Q

secondary lymphoid organs

A

lymph nodes, spleen

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4
Q

Functions of lymphatic system

A

Drain excess intersitial fluid
absorb digested lipids from small intestine
major location for “adaptive” immune responses
Site of resident macrophages

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5
Q

lymph

A

located within lymphatic vessels and lymphatic tissue

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6
Q

Intersitial fluid

A

found between cells

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7
Q

Plasma

A

helps to form interstitial fluid

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8
Q

How is lymph formed?

A

Once intersistial fluid passes into lymphatic vessel it becomes lymph

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9
Q

The thoracic duct joins the venous system as it empties into the ______vein. It drains what general body areas?

A

Left subclavian jugular

neck, head, chest and upper limbs

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10
Q

The right lymphatic duct joins the venous system as it empties into the ______vein. It drains what general body areas?

A

Right internal jugular

Upper right side of body

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11
Q

How does blockage of lymph flow cause lymphedema

A

if lymph is blocked it can’t accept any additional ISF and excess ISF = Edema

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12
Q

List some factors that assist the flow of lymph

A

Valves
protein
skeletal muscle pumps
respiratory pumps

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13
Q

Where is the thymus gland located?

A

mediastinum between sternum and aorta

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14
Q

Function of thymus gland

A

promotes maturation of T-Cells

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15
Q

Where is the spleen?

A

left hypochondriac region between stomach/diaphram

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16
Q

functions of spleen

A

filters blood, helps immune system recognize foreign antibodies, destroys blood-born pathogens

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17
Q

Functions of lymph nodes

A

filter

slows the flow

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18
Q

lymph nodes filter

A

lymph

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19
Q

spleen filter…

A

blood

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20
Q

what tonsil is commonly referred to as adenoids?

A

pharyngeal

(is single, located in the nasopharynx

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21
Q

what tonsil is paired, located near the base of the tongue?

A

Lingual

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22
Q

What tonsil is paired, located in the posterior oral cavity; usually what is referred to with the term “tonsils”

A

Paletine

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23
Q

what is the functional significance of the location of the tonsils?

A

to participate in immune responses against inhaled or ingested foreign substances

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24
Q

Second line of defense

A

internal antimicrobial substances, phagocytes, natural killer cells, inflammation, and fever.

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25
Protein produced by lymphocytes, macrophages, and fibroblasts.
interferon
26
group of inactive proteins in blood plasma and on plasma membranes, complement or enhance certain immune reactions; causes cytosis (bursting) of microbes, contributes to inflammation
Complement
27
most important phagocytes
neutrophils and macrophages
28
phagocytosis is a defense mechanism because.....
they injest unwanted debris and play a role in adaptive immunity
29
general function of inflammatory response
defensive response of the body to tissue damage
30
what two types of white blood cells are the significant phagocytes in the inflammatory response
neutrophils and macrophage (monocytes)
31
arrives at scene first but does not last long
neutrophils
32
arrives later but is effective for a longer period?
Macrophage
33
Four cardinal signs of inflammation
Redness pain heat and swelling
34
antigen
foreign substance-ability of the body to defend itself against invading agents
35
examples of antigens
MHC, Helper T, B Cell, cytotoxic
36
major cell type of the adaptive immune response
B and T Cells
37
where do B and T cells develop?
Primary lymphatic organs | red bone marrow and thymus
38
A particular lymphocyte is capable of recognizing____different type of antigen
ONE
39
A lymphocyte gains the capacity to recognize a particular antigen _____contact with it
AFTER
40
responsible for cell mediated immune response originate from stem cells in red bone marrow mature in thymus attack invaders directly two types are helper and cytotoxic cells attack antigen found within body cells produce memory cells
T-lymphocytes
41
Originate from stem cells in red bone marrow mature in red bone marrow responsible for the humural immune response secrete antibodies when activated, become plasma cells attack antigen found outside of body produce memory cells
B-lymphocytes
42
what is the function of helper t cells?
aid the immune system responses of both cell mediated and antibody mediated immunity
43
small hormones that stimulate or inhibit many normal cell functions, like cell growth and differentiation
cytokines
44
what cells produce cytokines
lymphocytes and antigen presenting cells.
45
secretes antibodies formed from activation of B-cells involved in humural immunity
Plasma
46
Stimulates multiplication of both B and killer T cells | also known as CD4 cells.
Helper T Cells
47
destroys antigen-bearing cells by disrupting plasma membrane involved in cell-mediated immunity also known as CD8 also known as killer T cells
Cytotoxic T-Cells
48
engulf and display antigens on their surface MHC's
antigen-presenting cell | dendritic, B-Cells, macrophages
49
mediator of secondary immune response
Memory
50
several ways in which antigen-antibody complexes can destroy antigens
1) Neutrolizing antigen (antitoxins) 2) Immobilzing bacteria 3) agglutinating and precipitating antigen 4) activating complement 5) Enhance phagocytosis
51
Three functions of activated complement proteins
Destroy microbes by causing phagocytosis, cytolysis, and inflammation causes inflammation prevents excessive damage to body tissue
52
First exposure to a specific antigen result in the _____immune response. Subsequent exposure to the same antigen results in the _____immune response
Primary | Secondary
53
Immunity is provided by_____cells and involves the activities of the _____immune response
B and T cells | Secondary
54
contracting and recovering from a case of the measles
natural active immunity
55
receiving a flu shot
Artificial active immunity
56
receiving and injection of gamma globulin
Artificial passive immunity
57
newborn immunity gained from placental transfer of maternal antibodies or in mother's milk
Natural passive immunity
58
May be life-long
Natural artificial and natural active
59
Temporary immunity
Natural Passive
60
gained through action of memory cells
natural active and artificial active
61
receiving an injection of tetanus antitoxin
artificial passive