Lymphatic/immune Flashcards
Innate immunity
(Non-specific)
1)block entry into blood
2)non-specific-cell meditated responses to rid
of solid pathogen.
*response is not strain specific (attack all)
*neutrophils, eosinophils, basophils,
monocytes, leukocytes, epidermis, NK
cells
Lymphatic functions:
1) Assists the CV system by collecting filtrate
(plasma) that did not get reabsorbed.
2) Assist the immune system by:
* help maturing some leukocytes
* provide mobility for leukocytes
* helps destroy leukocytes (old/worn out)
3) Assists the digestive system by helping
package large hydrophobic fats.
Adaptive immunity
(Specific, acquired)
1) B-lymphocytes
2) T-lymphocytes
3) Antibodies: y shaped protein = 4 polypeptides= 2 heavy chain & 2 light chain
6 functions of activated antibody:
1) agglutination
2) neutralization
3) precipitation
4) Opsonization
5) Activation of natural killer cells
6) Activate the complement system
Agglutination
Bind & clump together antigen-containing pathogen
Neutralization
Pathogen covered with antibodies–> block normal infection activity of pathogen
Precipitation
Clumped antigens fall out of solution; preventing movement through BV
Opsonization
Antibody serves as a beacon/flag to our phagocytize cells
Activation of Natural Killer cells
Destroy abnormal cells
Activate the complement system
30 complement proteins in blood which bind to activated antibodies.
Functions of component:
1) further signal opsonization
2) result in the formation of infected cell or
pathogen
3) inflammation
4) Attach pathogen to an RBC erythrocyte –>liver/spleen–>rid of pathogen
Tonsils
Defense against pathogens in air/food
Pharyngeal/palatine/lingual
Thymus function
Maturation of T lymphocytes
Spleen function
Reservoir for platelets-removes erythrocytes
Filters blood for foreign materials
Appendix function
No function? Safe house for bacteria?
Lymphatic vessels function
Bring lymph into lymph nodes
Lymph nodes
Monitors foreign materials
Right lymphatic duct
Drains lymph from upper right region
Thoracic duct
Drains lymph from the left side of body & the rest
Cisterna chili
Receives lymph “chili” which drains small intestine of GI tract
