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Oncology AM > Lymphadenopathy > Flashcards

Lymphadenopathy Flashcards

1
Q

What does a localised and painful lymph node signify?

A

Bacterial infection in draining site

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2
Q

What may a localised and painless node signify?

A

Rare infection- TB
Metastatic carcinoma of draining site
Lymphoma
Reactive node of unknown cause

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3
Q

What does a metastatic node feel like?

A

Hard, painless

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4
Q

What does a lymphoma node feel like?

A

Rubbery, painless

Local or generalised

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5
Q

What may generalised and painful nodes signify?

A

Viral- EBV, CMV, HIV

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6
Q

What may generalised and painless nodes signify?

A 
Lymphoma
leukaemia
Connective tissue disease
Reactive node of unknown cause
Drugs
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7
Q

What connective tissue diseases can cause lymphadenopathy?

A 
SLE
RA
Sarcoid
Dermatomyositis
Sjogren's
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8
Q

What drugs can cause lymphadenopathy?

A

Phenytoin

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9
Q

When are cervical nodes more commonly seen?

A

Infection

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10
Q

What nodes have a high suspicion of malignancy?

A

Supraclavicular

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11
Q

What is Virchow’s node?

A

Left supraclaviular node

Associated with abdominal/thoracic cancer

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12
Q

What may unilateral mediastinal nodes signify?

A

Infection

malignancy

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13
Q

What may bilateral mediastinal nodes signify?

A

Sarcoid
Chronic granulomatous disease
Lymphoma

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14
Q

What is a common and concerning cause of lymphadenopathy?

A

HIV

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15
Q

What are some common and less concerning causes of lymphadenopathy?

A

Viral infection- EBV, CMV, VZV, HZV

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16
Q

What are some uncommon but concerning causes of lymphadenopathy?

A

Lymphoma- Hodgkin or non-Hodgkin

Metatstis solid tumour

17
Q

What are some uncommon and less concerning causes of lymphadenopathy?

A 
CLL
Drugs
Hepatitis
TB
BActerial infection
Toxoplasmosis
Connective tissue disease
18
Q

What investigations should be done for ly,phadenopathy if concerned?

A

Bloods
CXR
Persistent- FNA, CT, PET

19
Q

What bloods should be done for lymphadenopathy?

A

FBC, U&Es, LFTs, ESR, CRP
Blood film
Monospot test
HIV test

20
Q

How are Hodkin and non-Hodgkin diagnosed?

A

FNA

Hodgkin= Reid Steinberg cells, Owl sign

Oncology AM (6 decks)

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