Lymphadenopathy

Question 1

Causes of generalized lymphadenopathy

Answer 1

MIAMI

Malignancies (lymphoma, leukemia, metasta)

Infection (brucellosis, bartonellosis, CMV, HIV, EBV, streptococci, rubella, tuberculosis, syphilis)

Autoimmune (SLE, arthritis)

Miscellaneous (Kawasaki doessss, sarcoidosis)

Iatrogenic (serum sicknes, drugs)

Question 2

EBV symptoms

Answer 2

Malaise, fatigues, Fever, sweats
Sore throat, dysphasia
Anorexia
Nausea, headaches, photophobia

Signs 
Splenomegaly, hepatomegaly
Bradycardia 
Periorbital edema
Palatal enanthem
Rhinitis
Mucous membrane swelling, reddened throat and tonsils with whitish coating

Question 3

Complication of EBV

Answer 3

Acute

• Rash
• airway obstruction
• splenic rupture
• lemirre syndrome

Delayed

• chronic active EBV infection
• oral hairy leukopenia
• lymphoproliferative disorders

Question 4

Kawasaki Disease diagnosis criteria

Answer 4

A- 5days of fever 
B- plus four or five 
\+ erythema of lips or oral cavity or cracking of lips
\+ Rash on trunk
\+ Swelling or erythema of hands or feets
\+ red eyes (conjunctivitis)
\+ swollen lymph nodes 

C- disease cannot be explained by sone other known disease process

Question 5

KD lab finding

Answer 5

leukocytosis with left shifting in WBC, elevated CRP, ESR, throbocytosis

Elevated ferritin

Platelet counts rise

Normocytic, normochromic anemia

Hyponatremia

Mild to moderate elevation of transminases

Question 6

Treatment of KD

Answer 6

IV IG 2g/ kg administered as single infusion over 8 to 12 hrs
And aspirin 30 to 50mg/kg daily divided into four doses

Question 7

PFAPA

Answer 7

Periodic Fever
Aphthous stomatitis
Pharyngitis
Cervical adenopathy