Lymph system quiz Flashcards

0
Q

Non Specific Resistance (innate defense) 1st line

A

Skin, Mucous membranes, Mucus, Hairs, cilia, Lacrimal apparatus, saliva, urine, defecation and vomiting

Sebum, lysozyme, gastric juice, vaginal secrations

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1
Q

Chemicals increase Vasodilation and increased permeability

A

Histamine (by must cells, basophils and platelets, stimulated by Neutrophils and Macrophages)
Kinins (bradykinin, chemotactic agents for phagocytes)
Prostaglandins (by damaged cells, intensify the effect of histamine and kinds, emigration of phagocyte)
Leukotriens (LTs, produced by basophils and must cell, adherence of phagocytes to pathogens)
Complement

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2
Q

Non Specific resistance (Innate defense) 2nd line

A
Antimicrobial Proteins (interferons, complement system, transferrins), 
Natural killer (NK) cells
Phagocytes (Neutrophils and Macrophages)
Inflammation
Fever
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3
Q

Interferon released by

A

virus infected cells to interfere with viral replication (antimicrobial substances)

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4
Q

Complement made up of

A

Antimicrobial substance: normally inactive proteins in blood plasma and on plasma membranes
Cytolysis of microbes, phagocytosis (opsonization), contribution to inflammation

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5
Q

Iron-binding proteins

A

Antimicrobial substances

Transferrin, lactoferrin, ferrietin, hemoglobin

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6
Q

Antimicrobial proteins

A

Antimicrobial substances: Dermicidin, defensins, catherlicidins, thrombocidin

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7
Q

immunoglobulins is

A

antibody, glycoproteingroup contain 4 polypeptide chains

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8
Q

Hapten is an antigen

A

Reactivity but not immunogenicity

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9
Q

Monocytes differentiate to

A

Wandering macrophage

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10
Q

Natural killer cells are

A

lymphocytes

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11
Q

lymphatic vessel is most similar to that of a

A

vein

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12
Q

interleukin 1

A

by macrophage, proliferation of helper T Cells, acts on phypohtalamus to cause ever

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13
Q

interleukin 2

A

by helper T cells, costimulates proliferation of helper T cell,

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14
Q

Interleukin 4

A

by helper T cells, costimulator for B cells, causes plasma cell to secrete IgE antibodies,

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15
Q

Interleukin 5

A

by helper T cells, costimulator for B cells, causes plasma cells to secrete IgA antibodies

16
Q

Interleukin 6

A

Produced by helpter T cells, B cell differentiation into plasma cells

17
Q

Tumor necrosis factor

A

by macrophages, stimulates accumulation of neutrophils and macrophages at the sites of inflammation and stimulates their killing of microves

18
Q

Macrophage migration inhibiting factor

A

produced by cytotoxic T cells, prevents macrophages from leaving site of infection

19
Q

activation of T cells

A

First signal T cell receptors recognize and bid to specific foreign antigen fragments that are presented in antigen -MHC complexes.
Second signal if it binds to foreign antigen and at the same time receives costimulation such as interleukin 2

20
Q

Antigen presenting cells

A

Dendritic cells, macrophages, B cells

21
Q

Cytotoxic T Cells activated by

A

Interleukin 2 or other cytokines activated by other active T helper cells

22
Q

Cytotoxic T cells kills

A

infected target cells, cancer cells, and transplanted cells

23
Q

Cytotoxic T cells releases

A

Perforin or granulysin to pierces the cell

Granzyme - protein digesting enzymes that trigger apoptosis, with microbes killed by phagocytes

Lymphotoxin - activated enzyme in the target cell - DNA fragments