Lymph

Question 0

Self antigen vs non self antigen

Answer 0

Self- antigens that the body recognizes as his own body cells

Non self- foreign cells that have entered the body (get destroyed)

Question 1

Nk cells

Answer 1

immune surveillance

Attack and destroy bacteria,host cells that are infected or cancerous

-second line of defense (nonspecific)

Question 2

T (lymphocytes) cells

Answer 2

• matures in the thymus (depend on thymus hormones)

- second line of defense (specific)

Question 3

B (lymphocytes) cells

Answer 3

• connective tissue cells/secretes antibodies by becoming plasma cells.
• mature in bone marrow
• needs T cells in lymph to react to antigens
• second line of defense (specific)

Question 4

Macrophages

Answer 4

• large phagocytic cells,
• develop as monocytes the came from the bloodstream
• phagocytize debris, dead cells and foreign matter (displays fragments on surface for T cells)
• antigen presenting cells
• nonspecific, second defense

Question 5

Dendritic cells

Answer 5

• engulf foreign matter by receptor mediated endocytosis (function like macrophage)
• second defense nonspecific

Question 6

Reticular cells

Answer 6

Stationary APCs that contribute to connective tissue frame work of lymphatic organs

-second defense nonspecific

If bound to our particular antigen then starts deleting it and those like it

Question 7

Primary immune response

Answer 7

Nonspecific, no prior exposure, skin (dry nutrient poor) and

mucous membranes(lysosomes destroys bacteria)

Question 8

Sencondary immune response

Answer 8

Inflammation, fever and phagocytic cells, immune cells

Nonspecific

Question 9

Third immune response

Answer 9

Specific

Prior exposure, protects against pathogens, vaccinations

Question 10

Intracellular response

Answer 10

Virus ENTERS cell, cell kills virus then becomes a APCs informing other cells

Question 11

Extracellular immune response

Answer 11

Bacteria is ENGULFED by a cell such as a macrophage and then becomes an APC

Question 12

Interferons

Answer 12

Released form infected cell by virus, tells other cells not to make mRNA so it doesn’t reproduce

Tells cells to kill off infected host cells

Question 13

MALT

Answer 13

External barrier

Mucous associated lymphatic tissue

Question 14

GALT

Answer 14

External barrier

Gut associated lymphatic tissue

Question 15

Cytokines

Answer 15

Small proteins that regulate inflammation and immunity (category)

Question 16

Heparin

Answer 16

Pathogens are in a fluid pocket surrounded by clot

Prevents interference on damaged tissue

Question 17

Chemotaxis

Answer 17

Leukocytes are attracted to chemtactic chemicals

Like EMTs, first responders

Question 18

Monocytes

Answer 18

Clears out area where damage was made

Question 19

MHC protein

Answer 19

-major histocompatiblaty complex

MHC 1 found on any nucleated cell intercellular pathogen (B cells T cells macrophages )

MHC 2 antigen presenting cell done extracelluar

Question 20

Epitopes

Answer 20

are antigen determinants,

A place where antibodies bind themselves

7-8 amino acids long

Question 21

Negative Selection

Answer 21

keeps it from circulating in blood stream and destroying our tissues

Question 22

Interleukins

Answer 22

• chemical messenger of leukocytes

Question 23

Cytotoxic cells

Answer 23

Cd8 cell, (cytotoxic T cell) carry out direct attack -MHC 1=8

Cd4 cells- are helper T cells, promotes t and B cell action (nonspecific defenses)
-MHC 2=8