Lyme Disease

Question 1

Signs & Sx

Early Infection (one or more may be present at different times during infection)

Answer 1

• Red rash (erythema migrans)
• Flulike symptoms (fever, headache, stiff neck, fatigue)
• Migratory musculoskeletal pain (joints, bursae, tendons, muscle, or bone)

Neurologic symptoms:
• Severe headache (meningitis)
• Numbness, pain, weakness of extremities
• Poor motor coordination
• Cognitive dysfunction: Memory loss, difficulty
in concentrating, mood changes, sleep
disturbances
Less Common Symptoms
• Eye problems such as conjunctivitis
• Heart abnormalities and myocarditis

Question 2

Late I n f e c t i o n (months to years after infection)

Answer 2

• Arthritis, intermittent or chronic
• Encephalopathy (mood and sleep disturbances)
• Neurocognitive dysfunction
• Peripheral neuropathy