LYME DISEASE

Question 1

Lyme disease is caused by

Answer 1

Borrelia burgdorferi

Question 2

The vector of lyme disease is

Answer 2

Ixodes ticks

Question 3

Do everyone bitten by the tick gets infected?

Answer 3

No only rarely people are infected due to spirochateocidal activity in serum

Question 4

Clinical feature stages

Answer 4

Stage 1: spring/summer
Stage 2: several weeks or months later
Stage 3: several months/ years later

Question 5

Stage 1 clinical fratures

Answer 5

Flu like symptoms
Arthralgia
Skin rash (erythema chronicum migrans)

Question 6

Stage 2 clinical features

Answer 6

Subacute lymphocytic meningitis
Subacute encephalitis
Cranial nerve involved- facial nerve palsy
Peripheral neuropathy

Question 7

Bannwarth’s syndrome

Answer 7

Subacute demylinating and axonal sensory/motor neuropathy with severe radiculitis

Question 8

CSF examination in stage 2

Answer 8

Lymphocytosis
Oligoclonal bands
Increased immunoglobulin
Increases anti burgdorferri antibodies

Question 9

Stage 3 clinical features

Answer 9

Arthritis
Diffuse CNS involvement
Chronic/subacute encephalitis
Focal brain disease
Psychiatric disease with fatigue and diffuse muscle pain

Question 10

Diagnosis

Answer 10

IFA
ELISA
PCR
MRI with subcortical white matter lesion

Question 11

Treatment

Answer 11

Antibiotics
Penicillin
Tetracycline
Erythromycin