Lyme, Babesiosis, Ehrlichiosis and Anaplasmosis, RMSF Flashcards
Early lyme disease treatment
Doxy, Amoxicillin, Cefuroxime
Late carditis or neurologic disease in lyme disease treatment
IV penicillin or IV ceftriaxone
Arthritis and facial nerve palsy in lyme disease treatment
doxy
Findings on blood smear for babesiosis
Intraerythrocytic parasites in ring or tetrad formation (maltese cross)
In babesiosis cases of low parasitemia consider
PCR for Babesia DNA
Treatment of Babesiosis
Monitor Asymptomatic patients for 3 months
Atovaquone plus azithromycin for symptomatic patients or persistent parasitemia after 3 months
Treatment of severe Babesiosis
Clinda + quinine
Anaplasma infect
leukocytes
E. chaffeensis causes
human monocytic ehrlichiosis (HME)
A. phagocytophilum causes
human granulocytic anaplasmosis (HGA)
Notable findings for Ehrlichiosis and Anaplasmosis
Leukopenia, thrombocytopenia
Presence of morulae (clumps of organisms in the cytoplasm of leukocyte)
Testing for Ehrlichiosis and Anaplasmosis
whole blood PCR
Three organisms transmitted by black legged deer tick/Ixodes tick
HGA, Lyme disease, Babesiosis
Treatment for HME and HGA
Doxycycline
RMSF Diagnosis
Immunohostochemistry or PCR of skin biopsy