Lupus Vulgaris Flashcards
What is Lupus Vulgaris?
Lupus vulgaris are painful cutaneous tuberculosis skin lesions with nodular appearance.
Lesion appear in normal skin as a result of:
* Direct extension of underlying tuberculous foci
* Lymphatic or haematogenous spread
* After primary inoculation
* BCG vaccination
* Scars of old scrofuloderma
Presentation of Lupus Vulgaris?
Most often on the face around nose, eye lids, lips, cheeks & ears
Lesions are usually solitary, small, sharply marginated, red-brown papules of gelatinous consistency (apple-jelly nodules) that slowly evolve by periperal extension & central atrophy into large plaques
Treatment for Lupus Vulgaris?
Antitubercular regimen usually involves the concurrent use of four drugs- isoniazid, rifampicin, pyrazinamide, & either ethambutol or streptomycin 0 for a period of 8 weeks. This quadruple threapy is followed by a 16 week course of isoiazid and rifampicin