Lupus

Question 1

SLE most commonly occurs in

Answer 1

women
Asian, African, Caribbean and Hispanic ethnicity
Young to middle-aged

Question 2

complications of SLE that shorten life expectancy

Answer 2

Cardiovascular disease and infection

Question 3

SLE is characterised by

Answer 3

anti-nuclear antibodies (ANA)

Question 4

FBC findings in SLE

Answer 4

anaemia of chronic disease, low white cell count and low platelets

Question 5

During active SLE C3 and C4 levels are

Answer 5

decreased

Question 6

Antibody with highest specificity to SLE

Answer 6

Anti-double stranded DNA (anti-dsDNA)

Question 7

First line management of SLE

Answer 7

Hydroxychloroquine
NSAIDs
Steroids

Question 8

discoid lupus lesions are

Answer 8

photosensitive

Question 9

discoid lupus is associated with what other skin changes

Answer 9

scarring alopecia
hyper / hypopigmentation

Question 10

lesions of discoid lupus are

Answer 10

inflamed
dry
erythematous
scaling

Question 11

treatment of discoid lupus

Answer 11

Sun protection
Topical steroids
Intralesional steroid injections
Hydroxychloroquine

Question 12

Features of drug induced lupus

Answer 12

arthralgia
myalgia
malar rash
pleurisy

Question 13

Antibody findings in drug induced lupus

Answer 13

ANA positive
dsDNA negative

Question 14

Most common causes of drug induced lupus

Answer 14

procainamide
hydralazine
isoniazid
phenytoin