Lupus Flashcards

1
Q

ANTIBODIES:-

SLE

Drug SLE

Diffuse SSc

Limited SSc

Sicca

MCTD

A

Anti-dSDNA Anti-Smith

Anti-Histone

SCL70 (Anti topoisomerase 1)

Anti centromere

Anti-Ro/La

Anti-U1 RNP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

SLE MCCD

A

GN (Early)

Thromboembolic events/ Pericarditis (Late)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

SLE fatal signs

A

GN
Pericarditis
Coagulopathy
Seizures

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Arthropathy SLE

A

Jaccouds

Assymetrical

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

SLE clinical features mnemonic

A

SAC SONG CHTL

Synovitis
Acute rash (malar)
Chronic rash (discoid)

Serositis (pleura>pericardium)
Oral/Nasal ulcers
Non Scarring Alopecia
GN

CNS
Hemolytic Anemia
Thrombocytopenia
Leucopenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

SLE R/f

A

TREX-1

Klinefelter

EBV

UV and silicosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

SLE Markers

A
ANA (m.s)
Anti-dsDNA (msp)
Anti -Sm
APLA
Anti platelet
Anti neuronal anti ribosomal
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

SLE rx

A

Iv ch3pred
Oral ch3pred

Mild flare: oral + steroid sparing : hcq mycomof

Refrac SLE: belimumab(BAF/BLys inhibitor) rituximab

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Ssc r/f

A

Parvo b19
Cmv
Silicosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Ssc first sign

A

Raynauds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Ssc cardinal signs

A

Inflammation
Microangiopathy
Sclerosis of skin and organs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Ssc clinical features (late)

A

Thickened skin
Shortening of digits
Fish mouth/ mask face

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Ix raynaud

A

Nailfold capillaryscope

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Limited vs Diffuse ssc

A

Distal elbow. Proximal elbow + organs
CREST. PaH M.multiplex. RPGN
Calci cutis. ILD-NSIP (rx iloprost)
Raynaud
Esophagus
Sclerodactilyty
Telengectasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Ssc mccd

A

PAH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Sjogren Ix

A

Eye: schirmer or Rose bengal

Saliva: Iontophoresis

17
Q

Sicca types

A

1° : bad px/extraglandular++/lymphoma+

18
Q

Sicca salivary rx

A

Pilocarpine