Lung Pathology Flashcards

1
Q

what are the changes in lobar pneumonia

A

consolidation of the affected part and filling of alveolar spaces. the whole lobe is affected at the same time. blood vessels surrounding capillaries are dilated due to inflammatory response, leading to release of neutrophils, along with fibrin and fluid, into the alveolar spaces- this is a sign of an acute inflammatory response

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2
Q

where does mesothelioma occur in the lung?

A

pleural

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3
Q

what are pathology in the lower airways

A

pneumonia, abscess, emphysema, asbestosis, adenocarcinoma

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4
Q

exudate

A

fluid containing proteins i.e. fibrin. it is the technical name for puss

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5
Q

types of

A

lobar and bronchopneumonia

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6
Q

what is the most common pathogen causing peunomia

A

streptococcus pneumonia

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7
Q

what is the most common pathogen causing peunomia

A

streptococcus pneumonia

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8
Q

what are the stages of lobar pneumonia

A

congestion: lung is red, fluid in alveoli

red hepatisation: texture of fresh liver, RBC and fibrin fill alveoli

grey hepatisation: lung cooked liver, macrophages and lymphocytes in alveoli

resolution: lung to normal, purulent exudate removed

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9
Q

what is bronchopneumonia

A

whole lobe is not consolidated, rather there are patches of infection and puss

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10
Q

what is dyspnoea

A

impairment of gas exchange, which leads to difficulty breathing

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11
Q

what does suppurative exudate lead to

A

cough and mucopurulent sputum

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12
Q

what is an abscess

A

severe infection due to localised puss, causing destruction of underlying tissue. wound healing around the outside to seal off abcess to stop spreading to surrounding tissue

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13
Q

what is haemorrhage

A

bleeding in tissue

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14
Q

atypical pneumonia

A

interstitial tissue that surround the alveoli, impairing gas exchange and reducing lung capacity. leads to dry and unproductive cough (no puss)

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15
Q

what is pulmonary embolism

A

lodging of emboli in the lung. most commonly from venous thrombosis from lower extremities (i.e. DVT). often they are small and there are multiple emboli

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16
Q

what is an embolus

A

foreign material in circulation eg. thrombus, fat globule, air bubble, gas, tumour cells, foreign material

17
Q

small vs large pulmonary embolism

A

60-80% are small and clinicaly silent. may cause infarction or haemorrhage of lung tissue. large (saddle) emboli blocks pulmonary artery at the bifurcation (starts to fold up) complete block of blood flow to emboli leading to acute sudden tissue death

18
Q

small vs large pulmonary embolism

A

60-80% are small and clinicaly silent. may cause infarction or haemorrhage of lung tissue. large (saddle) emboli blocks pulmonary artery at the bifurcation (starts to fold up) complete block of blood flow to emboli leading to acute sudden tissue death

19
Q

obstructive

A

can occur at any point of the airway, increases resistance to airflow due to partial/complete obstruction. mucous enhances obstruction I.e in asthma. others: emphysema

20
Q

restrictive

A

reduce expansion of lung, elastin taken over with fibrosis. emphysema

21
Q

resources

A

robin’s textbook

Medscape (website)

22
Q

what is fibrosis

A

collagen deposition