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1MB Respiratory (My version) > Lung Cancer > Flashcards

Lung Cancer Flashcards

1
Q

The prevalence of lung cancer is low. True/False?

A

True

Incidence is high, but patients do not live for very long

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2
Q

What symptom arises due to damage of the recurrent laryngeal nerve?

A

Hoarse voice

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3
Q

Pancoast tumours typically affect which part(s) of the lung?

A

Top

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4
Q

Common sites of lung cancer metastases (5)

A 
Liver
Brain
Bone
Adrenals
Skin
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5
Q

Which LFT is particularly abnormal in liver metastasis?

A

Alkaline Phosphatase (ALP)

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6
Q

How can hypercalcaemia arise?

A

Tumour produces a substance which mimics the effects of parathyroid hormone

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7
Q

Lung diseases causing clubbing (ABCDEF)

A 
Abscess
Bronchiectasis
Cystic Fibrosis
Don’t say COPD
Empyema
Fibrosis
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8
Q

Name the 4 types of lung tumour classifications

A

Adenocarcinoma
Squamous cell carcinoma
Small cell carcinoma
Large cell carcinoma

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9
Q

TTF-1 is expressed only in adenocarcinoma. True/False?

A

False

Also in small cell carcinoma

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10
Q

P63 is expressed in squamous cell carcinoma. True/False?

A

True

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11
Q

Which type of lung cancer has the poorest prognosis?

A

Small cell carcinoma

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12
Q

Which type of lung cancer is responsive to chemotherapy?

A

Small cell carcinoma

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13
Q

What is the treatment of choice for non-small cell carcinoma?

A

Surgery

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14
Q

K-ras and EGFR mutations occur in which type of lung tumour?

A

Non-small cell cancer

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15
Q

What characteristic of small cell carcinoma makes it susceptible to chemotherapy?

A

Rapid growth

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16
Q

Surgery is only indicated if the disease is localised. True/False?

A

True

17
Q

What cells give rise to small cell carcinoma?

A

Neuroendocrine cells

18
Q

Small cell carcinomas are more common in non-smokers. True/False?

A

False

19
Q

Which lung cancer type is more common in non-smokers?

A

Adenocarcinoma

20
Q

Which is the most common type of lung cancer?

A

Squamous cell carcinoma

21
Q

How can small cell carcinoma commonly be treated?

A

Chemotherapy

22
Q

Who gets radical radiotherapy?

A

Early NSLC patients with adequate lung function but where surgery is not possible

1MB Respiratory (My version) (13 decks)

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