Lung Cancer Flashcards
TTF-1 (thyroid transcription factor) is expressed most characteristically in what type of carcinoma?
small cell and adenocarcinoma
P63 is expressed in what type of carcinoma?
squamous
What type of lung cancer is the worst?
small cell
What may often show K-ras mutation
lung adenocarcinomas
What is a tyrosine kinase inhibitor which shows activity in some NSCLC patients?
gefitinib
Which lung cancer is most common?
squamous
Which lung cancer is most deadly?
small cell
Where is small cell located?
across the hilium/central
Where are adenocarcinomas of the lung?
peripheral
Why do adenocarcinomas present late?
as they are peripheral, they are less likely to cause obstruction symptoms
Where are large cell lung cancers located?
centrally
Where are squamous cell lung cancers located?
centrally/ across large bronchi
How is lung cancer diagnosed?
bronchoscopy with biospy
Which type of lung cancer do smokers get?
squamous
Which type of lung cancer is known for hypercalcaemia?
squamous
