Lung Flashcards
Tidal Volume (TV)
Normal breathing 500ml
- Controlled by pneumotaxic center
- Starts Herring breuer reflex
Inspiratory Reserve volume (IRV)
Forced inspiration 3000ml
- Apneustic center in pons–>turns off pneumotaxic
- Shuts down Herring breur reflex
Expiratory Reserve volume (ERV)
Forced expiration 1100ml
*controlled by rectus abdominus
Residual volume (RV)
Keeps lung from collapse 1200ml
Inspiratory capacity
IRV+TV=3500ml
Functional Residual capacity
ERV+RV=2300ml
Vital Capacity
IRV+TV=ERV=IC+RV=4600ml
Total Lung volume
IRV+ERV+TV+RV=5800ml
Dead space
air in pulmonary tree not involved with gas exchange
Respiration is controlled by what nerve?
Dorsal motor nucleus of Vagus (X)
Alveolar pressure
Slightly negative–>Normal quiet inspiration
Atmospheric pressure
opposes alveolar pressure
Pleural pressure
Negative pressure: Keeps lungs open. Pressure of fluid in space between lung pleura and chest wall
Transpulmonary pressure
Difference between alevolar pressure and pleural pressure.
*Elastic forces in the lung AKA RECOIL PRESSURE
Respiratory Distress Syndrome
Lack of surfactant at birth
Bohr effect on inspiration at Lung
Hemoglobin binds 4O2–>releases H+, CO2, DPG, increases temp
*Shift to “Left=Shit to the Lung”
Bohr effect on inspiration at Tissue
Hemoglobin releases O2–>Binds H+, CO2, DPG, decreases temp
Lung is made of what type of tissue?
Pseudostratitifed ciliated columnar epithelium
Alveolar sacs are made of what type of tissue?
simple squamous epithelium
Which type of lung cell does gas exchange?
Type 1 pneuymocytes
What type of lung cell is responsible for surfactant production?
Type 2 pneumocytes
*Will lack in premature born children causing ARDS (Acute respiratory distress syndrome)
Macrophages of the lung?
Dust Cells
Fluid in lungs collect at what recess?
Costo-diaghragmatic recess
Which lung cells produce mucus?
Goblet cells
Respiratory acidosis
Increased H+, CO2,
Decreased O2
Purpose of Chlroide shift
to keep pH constant: 7.35-7.45
Decreased ventilation leads to Respiratory Acidosis or Alkalosis?
Resp. Acidosis
- Caused by holding breath
- tx: Urinate NH4+
Increased ventilation leads to Respiratory Acidosis or Alkalosis?
Resp. Alkalosis
- Cause by hyperventialtion
- tx: bag over head or excrete NaCO3 (bicarbonate)
Respiratory Alkalosis
Decreased H+, CO2
Increased O2
Metabolic Acidosis
Non lung
- Losing HCO3—>diarrhea, DM: ketoacidosis
- tx: hyperventilation blowing off CO2
- **if DM, smell ketones
Metabolic Alkalosis
Non lung
- Losing HCL->Bulimia
- Losing H+->Diuretics
- tx: Slow breathing